2-hydroxy-5-methyl-3-tritylbenzaldehyde | 223706-43-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxy-5-methyl-3-tritylbenzaldehyde
• 英文别名: 2-Hydroxy-5-methyl-3-tritylbenzaldehyde
• CAS: 223706-43-2
• 化学式: C₂₇H₂₂O₂
• 分子量: 378.47
• InChiKey: QSYQUWYMRVIMNA-UHFFFAOYSA-N

物化性质

• 熔点：
  152-153 °C(Solv: methanol (67-56-1))
• 沸点：
  486.8±40.0 °C(Predicted)
• 密度：
  1.174±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-hydroxy-5-methyl-3-tritylbenzaldehyde 在 三乙酰氧基硼氢化钠 、 sodium hydride 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 反应 48.17h， 生成 (N-(3,5-ditert-butyl-2-hydroxybenzyl)-N-(2-(diphenylphosphino)-benzyl)-N-bis(2-pyridylmethyl)amine)CoCl
  参考文献：
  名称：

  Zinc and cobalt complexes based on tripodal ligands: synthesis, structure and reactivity toward lactide

  摘要：

  一系列前配体（[L1]–[L6]）与钴和锌衍生物的配位化学已被研究。所有的配合物都通过多核核磁共振、元素分析以及单晶X射线衍射研究进行了表征。在130°C下，在钴和锌配合物的存在下，rac-乳酸内酯发生聚合反应，在无溶剂条件下生成具有可控分子量和窄分布宽度的聚合物。

  DOI：

  10.1039/c3dt52629a
• 作为产物：
  描述：

  三苯基氯甲烷 在 sodium 、 三氟乙酸 作用下， 反应 9.0h， 生成 2-hydroxy-5-methyl-3-tritylbenzaldehyde
  参考文献：
  名称：

  Degradation of β-O-4 model lignin species by vanadium Schiff-base catalysts: Influence of catalyst structure and reaction conditions on activity and selectivity

  摘要：

  In the pursuit of value-added products from the degradation of the abundant aromatic biopolymer lignin, homogeneous catalysis has the potential to provide a mild, selective route to monomeric phenols. Homogeneous vanadium catalysts have previously been shown to effectively cleave dimeric beta-O-4 model lignin compounds, with selectivity for C-C or C-O cleavage, or benzylic oxidation, depending on the ligand structure and oxidation state of the metal. In this study, a systematic kinetic investigation was undertaken in order to gain further understanding of the role of ligand structure and reaction conditions on the activity of vanadium Schiff-base catalysts towards a non-phenolic beta-O-4 model lignin dimer, and the selectivity of these species towards C-O bond cleavage. Catalytic activity was found to be increased by the addition of bulky, alkyl substituents at the 3'-position of the phenolate ring, whereas electron withdrawing substituents were found to dramatically reduce activity irrespective of their size. Selective depolymerization of a phenolic beta-O-4 dimer was also achieved. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cattod.2015.08.045

文献信息

• Synthesis of salicylaldehydes bearing bulky substituents in the positions 3 and 5
  作者：A. I. Kochnev、I. I. Oleynik、I. V. Oleynik、S. S. Ivanchev、G. A. Tolstikov

  DOI：10.1007/s11172-007-0170-5

  日期：2007.6

  4-disubstituted phenols with paraformaldehyde in the presence of SnCl4 and 2,6-lutidine afforded a number of new salicylaldehydes, containing bulky substituents (tert-butyl, 1-phenylethyl, 1-(4-tert-butylphenyl)ethyl, α-cumyl, and trityl) in the positions 3 and 5.

  在 SnCl4 和 2,6-二甲基吡啶的存在下，2,4-二取代酚与多聚甲醛反应得到许多新的水杨醛，其中含有大量取代基（叔丁基、1-苯乙基、1-（4-叔丁基苯基）乙基） 、α-枯基和三苯甲基）在位置 3 和 5。
• Exploring Electronic versus Steric Effects in Stereoselective Ring-Opening Polymerization of Lactide and β-Butyrolactone with Amino-alkoxy-bis(phenolate)-Yttrium Complexes
  作者：Miloud Bouyahyi、Noureddine Ajellal、Evgueni Kirillov、Christophe M. Thomas、Jean-François Carpentier

  DOI：10.1002/chem.201002779

  日期：2011.2.7

  of rac‐lactide (LA) and rac‐β‐butyrolactone (BBL) to provide heterotactically enriched poly(lactic acid)s (PLAs) and syndiotactically enriched poly(3‐hydroxybutyrate)s (PHBs), respectively, by means of a chain‐end control mechanism. Most of these polymerizations proceeded in a controlled fashion, giving polymers with narrow polydispersities and experimental molecular weights in good agreement with calculated

  一系列在酚环上具有R 1邻位取代基的甲氧基-氨基-双（酚）H 2（ONOO ）H 2（具有空间和电子特性）（R 1 = CMe 2 Ph，1 ; CMe 2 t Bu，3 ; CMe 2（4-CF 3 C ^ 6 ħ 4），5 ;器CPh 3，9 ;氯，10）已被合成并进一步用[Y N（SiHMe反应2）2 } 3 ]（THF）2 干净地得到相应的钇化合物[Y（ONOO ）N（SiHMe 2）2 }（thf）n ]（Y x）；确定了Y-3和Y-10的固态结构。这些酰胺基络合物已被用作外消旋丙交酯（LA）和外消旋rac的开环聚合（ROP）的引发剂-β-丁内酯（BBL）通过链端控制机制分别提供异规富集的聚乳酸（PLA）和间规富集的聚（3-羟基丁酸酯）（PHB）。这些聚合中的大多数以受控方式进行，得到具有窄的多分散性和实验分子量与计算值良好吻合的聚合物。R 1 邻位取代基的性质对聚合速率有更
• Salen complexes based on 1,4-diaminocyclohexane and their exploitation for the polymerisation of rac-lactide
  作者：Stuart L. Hancock、Mary F. Mahon、Matthew D. Jones

  DOI：10.1039/c3nj00111c

  日期：——

  In this paper we have prepared a series salen derived ligands based on a trans-1,4-diaminocyclohexane backbone. The ligands could be easily complexed to either Ti(IV) or Al(III) metal centres generating complexes with formulae Ti2(OiPr)6(L) and Al2(Me)4(L) respectively. The complexes were shown to be efficient initiators for the ring opening polymerisation of rac-lactide. The Al(III) complexes were more controlled than their Ti(IV) analogues, producing PLA with a moderate isotactic bias and narrow molecular weight distribution. The molecular weight of the resultant polymer, for the Al(III) system, could be controlled by the amount of benzyl alcohol added initiator indicating that these systems show immortal behaviour.

  在本文中，我们制备了一系列基于反式-1,4-二氨基环己烷骨架的沙林衍生配体。这些配体很容易与 Ti(IV) 或 Al(III) 金属中心络合，生成的配合物分别为 Ti2(OiPr)6(L) 和 Al2(Me)4(L)。这些配合物被证明是 rac-内酰胺开环聚合的高效引发剂。Al(III) 复合物比它们的 Ti(IV) 类似物更易控制，生成的聚乳酸具有适度的同素异形偏向和较窄的分子量分布。对于 Al（III）体系来说，生成聚合物的分子量可由添加的苄醇引发剂的量来控制，这表明这些体系表现出不朽的特性。
• Ring-opening polymerization of rac-lactide and α-methyltrimethylene carbonate catalyzed by magnesium and zinc complexes derived from binaphthyl-based iminophenolate ligands
  作者：Miao Huang、Chen Pan、Haiyan Ma

  DOI：10.1039/c5dt00158g

  日期：——

  the heteroleptic magnesium complex 4a has a four-coordinated metal core chelated by three donor atoms of the ligand and one bis(trimethylsilyl)amido group; however, the heteroleptic zinc complex 4b has a three-coordinated metal core chelated by two donor atoms of the ligand and one bis(trimethylsilyl)amido group, where the NMe2 group of the iminophenolate ligand is not coordinated to the zinc center

  一系列外消旋的2-[（（2'-（二甲氨基）联萘-2-ylimino）甲基] -4-R 2 -6-R 1-苯酚（L 1 H–L 6 H）与1当量反应。Mg [N（SiMe 3）2 ] 2或Zn [N（SiMe 3）2 ] 2形成三个杂硅镁硅酰胺基络合物[（L 4-6）MgN（SiMe 3）2 ]（4a：R 1 = R 2 =枯基; 5a：R 1 = CPh 3，R 2=我；图6a：R 1＝ CPh 3，R 2＝t Bu）和一种杂配硅烷基硅铝酰胺基络合物[（L 4）ZnN（SiMe 3）2 ]（4b：R 1＝ R 2＝枯基）。通过X射线衍射研究进一步证实了配合物4a，4b和同型锌配合物（L 5）2 Zn（5b'）的分子结构。固态的杂镁复合物4a具有被配体的三个供体原子和一个双（三甲基甲硅烷基）酰胺基螯合的四配位金属核；然而，杂配锌配合物4b具有被配体的两个供体原子和一个双（三甲基甲硅烷基）酰胺
• METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS
  申请人：Kol Moshe

  公开号：US20130310529A1

  公开（公告）日：2013-11-21

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a group 4 metal and a Salan ligand in the polymerization of alpha-olefins, is disclosed. The Salan ligand is characterized by a sequential diamino-containing skeleton unit which is non-symmetric, and the pre-catalysts can also be such that are devoid of a symmetry element. The disclosed polymerization results in alpha-olefin polymers such as polypropylene which are characterized by high levels of tacticity. Also disclosed are novel Salan ligands and novel complexes thereof with group 4 metals.

  揭示了在α-烯烃聚合中使用包括第4族金属和Salan配体的预催化剂的均相催化体系的用途。Salan配体的特点是具有非对称的顺序二氨基骨架单元，预催化剂也可以是不具有对称元素的。所揭示的聚合产物为α-烯烃聚合物，例如高度具有定向性的聚丙烯。还揭示了新型的Salan配体及其与第4族金属的新配合物。