1,4-bis<2-<2-<2-<2-(4-benzyloxyphenoxy)ethoxy>ethoxy>ethoxy>ethoxy>benzene | 134881-64-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,4-bis<2-<2-<2-<2-(4-benzyloxyphenoxy)ethoxy>ethoxy>ethoxy>ethoxy>benzene
• 英文别名: 1,4-bis<2-(2-(2-(2-(4-(benzyloxy)phenoxy)ethoxy)ethoxy)ethoxy)ethoxy>benzene；1,4-bis[2-[2-(2-{2-[4-(benzyloxy)phenoxy]ethoxy}ethoxy)ethoxy]ethoxy]benzene；1,4-bis[2-[2-[2-[2-(4-phenylmethoxyphenoxy)ethoxy]ethoxy]ethoxy]ethoxy]benzene
• CAS: 134881-64-4
• 化学式: C₄₈H₅₈O₁₂
• 分子量: 826.981
• InChiKey: ZHHCBLIUHYWLKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.86
• 重原子数：
  60.0
• 可旋转键数：
  34.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  110.76
• 氢给体数：
  0.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  1,4-bis<2-<2-<2-<2-(4-benzyloxyphenoxy)ethoxy>ethoxy>ethoxy>ethoxy>benzene 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 、 氯仿 为溶剂， 以90%的产率得到1,4-Bis<2-<2-<2-<2-(4-hydroxyphenoxy)-ethoxy>ethoxy>ethoxy>ethoxy>benzol
  参考文献：
  名称：

  Molecular Meccano. 2. Self-Assembly of [n]Catenanes

  摘要：

  The mutual molecular recognition between different: structural components in large rings has led to the template-directed synthesis of a wide range of catenanes composed of from two to five interlocked rings, The molecular self-assembly processes rely upon the recognition between (i) pi-electron rich and pi-electron deficient aromatic units and (ii) hydrogen bond donors and accepters, in the different components. In order to increase Our knowledge of the factors involved in such molecular self-assembly processes, a homologous series of [2]catenanes has been constructed using macrocyclic polyethers of the bis(p-phenylene)-(3n+4)-crown-n (n = 9-14) type as templates for the formation of the tetracationic cyclophane, cyclobis(paraquat-p-phenylene). Increasing the size of the tetracationic cyclophane to cyclobis(paraquat-4,4'-bitolyl) allows the simultaneous entrapment of two hydroquinone ring-containing macrocyclic polyethers affording a series of [3]catenanes, and one [4]catenane incorporating a cyclic dimer of the expanded cyclophane and three bis(p-phenylene)-34-crown-10 components. By analogy; increasing the number of hydroquinone rings in the macrocyclic polyether permits the self-assembly of more than one tetracationic cyclophane around the templates present in the macrocyclic polyether. In this context, the template-directed synthesis of two [3]catenanes, incorporating two cyclobis(paraquat-p-phenylene) components and either (i) tris(p-phenylene)51-crown-15 or (ii) tetrakis (p-phenylene)-68-crown-20, has been achieved and is reported. A combination of these two approaches has led to the successful self-assembly, in two steps, of a linear [4]catenane, together with a small amount of a [5]catenane: The creation of these intricate molecular compounds lends support to the contention that self-assembly is a viable paradigm for the construction of nanometer-scale molecular architectures incorporating a selection of simple components.

  DOI：

  10.1021/ja00109a011
• 作为产物：
  描述：

  2-[2-(4-苯基甲氧基苯氧基)乙氧基]乙醇 在 sodium hydride 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 19.0h， 生成 1,4-bis<2-<2-<2-<2-(4-benzyloxyphenoxy)ethoxy>ethoxy>ethoxy>ethoxy>benzene
  参考文献：
  名称：

  Amabilino, David B.; Anelli, Pier-Lucio; Ashton, Peter R., Journal of the American Chemical Society, 1995, vol. 117, # 45, p. 11142 - 11170

  摘要：

  DOI：

文献信息

• Ashton, Peter R.; Brown, Christopher L.; Chrystal, Ewan J. T., Angewandte Chemie, 1991, vol. 103, # 8, p. 1058 - 1061
  作者：Ashton, Peter R.、Brown, Christopher L.、Chrystal, Ewan J. T.、Parry, Keith P.、Pietraszkiewicz, Marek、et al.

  DOI：——

  日期：——
• Anelli, Pier Lucio; Ashton, Peter R.; Spencer, Neil, Angewandte Chemie, 1991, vol. 103, # 8, p. 1052 - 1054
  作者：Anelli, Pier Lucio、Ashton, Peter R.、Spencer, Neil、Slawin, Alexandra M. Z.、Stoddart, J. Fraser、Williams, David J.

  DOI：——

  日期：——