(2S,3S,4R,5R,6S)-2-[(3aS,8bR)-8b-hydroxy-2,3a-dihydro-1H-furo[2,3-b]indol-4-yl]-6-(hydroxymethyl)oxane-3,4,5-triol | 1380847-39-1

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核苷和核苷酸类似物
• 英文名称: (2S,3S,4R,5R,6S)-2-[(3aS,8bR)-8b-hydroxy-2,3a-dihydro-1H-furo[2,3-b]indol-4-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 1380847-39-1
• 化学式: C₁₆H₂₁NO₇
• 分子量: 339.345
• InChiKey: LVVHNZKAVHASOT-NDTOZGPPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  123
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  色醇 在 titanium(IV) isopropylate 、 叔丁基过氧化氢 、 L-(+)-酒石酸二异丙酯 、 溶剂黄146 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 23.0h， 生成 (2S,3S,4R,5R,6S)-2-[(3aS,8bR)-8b-hydroxy-2,3a-dihydro-1H-furo[2,3-b]indol-4-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
  参考文献：
  名称：

  Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta

  摘要：

  Makomotindoline (1) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline (1), its L-Glc isomer (2) and its aglycon (3) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.05.021

文献信息

• Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta
  作者：Tomohiro Suzuki、Jae-Hoon Choi、Takumi Kawaguchi、Kimiko Yamashita、Akio Morita、Hirofumi Hirai、Kaoru Nagai、Tomoyasu Hirose、Satoshi Ōmura、Toshiaki Sunazuka、Hirokazu Kawagishi

  DOI：10.1016/j.bmcl.2012.05.021

  日期：2012.7

  Makomotindoline (1) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline (1), its L-Glc isomer (2) and its aglycon (3) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth. (C) 2012 Elsevier Ltd. All rights reserved.