ketose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ketose
• 英文别名: 1,2,4,5,6-pentahydroxyhexan-3-one；DL-Xylo-3-hexulose
• 化学式: C₆H₁₂O₆
• 分子量: 180.158
• InChiKey: DWJZKGYQNOQQEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  118
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  聚合甲醛 在 1,3-二羟基丙酮 、 calcium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 生成 果糖 、 2-己酮醣 、 ketose 、 1,3,4-三羟基-3-(羟甲基)丁烷-2-酮
  参考文献：
  名称：

  Microbial Biomanufacturing Using Chemically Synthesized Non‐Natural Sugars as the Substrate

  摘要：

  摘要 利用生物质糖进行有价值材料的生物生产，作为一种环境友好型技术，正在引起人们的关注。然而，该技术在满足生产燃料和化工产品的巨大需求方面能力有限。为了在未来开发一种新型生物生产工艺来解决这些问题，本研究调查了利用谷氨酸棒杆菌（C. glutamicum）和化学合成的非天然糖溶液进行生物生产有价值物质的可行性。细胞以合成糖溶液为唯一碳源生长，并在限氧条件下产生乳酸盐。研究还发现，一系列化学反应产生的一些糖会抑制细胞的生长，因为事先去除这些糖会提高细胞的生长速度。本研究的结果表明，化学合成的糖类有可能解决微生物生物制造中未来生物质糖类供应的问题。

  DOI：

  10.1002/cbic.202300760

文献信息

• Catalytic effect of aluminium chloride on the example of the conversion of sugar model compounds
  作者：Martin Schwiderski、Andrea Kruse

  DOI：10.1016/j.molcata.2015.03.018

  日期：2015.6

  In this work, the catalytic effect of the Bronsted acid hydrochloric acid, the Bronsted base sodium hydroxide and the Lewis acid AlCl3 on the conversion of biomass derived carbohydrates is investigated. On the example of the glycolaldehyde conversion, it is shown that the Lewis acid catalyses the ketol-endiol-tautomerism, the dehydration, the retro-aldol-reaction and the benzilic-acid-rearrangement. The main products are C-4- and C-6-carbohydrates as well as their secondary products 2-hydroxybut-3-enoic acid 1 and several furans. Under the same reaction conditions hydrochloric acid catalyzes mainly the dehydration and sodium hydroxide the tautomerism and subsequent aldolization. (C) 2015 Elsevier B.V. All rights reserved.
• PRODUCTION OF GLYCOSYLATED PRODUCT IN HOST CELLS
  申请人：Inbiose N.V.

  公开号：EP4103727A2

  公开（公告）日：2022-12-21
• COMPOSITIONS AND METHODS RELATED TO EXCIPIENTS AND CANNABINOID FORMULATIONS
  申请人：Natural Extraction Systems, LLC

  公开号：US20210360947A1

  公开（公告）日：2021-11-25

  Various aspects of this patent document relate to beverage concentrates that comprise active ingredients, containers comprising beverage concentrates, and methods to prepare beverage formulations from beverage concentrates.
• [EN] COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS<br/>[FR] COMPOSITIONS ET PROCÉDÉS ASSOCIÉS À DES EXCIPIENTS PHARMACEUTIQUES
  申请人：NATURAL EXTRACTION SYS LLC

  公开号：WO2021158574A1

  公开（公告）日：2021-08-12

  This patent document describes excipients that allow certain bioactive agents that exist as hydrophobic molecules to be reformulated as anions that display improved hydrophilicity, which can improve the bioavailability and pharmacokinetics of broad classes of pharmaceuticals.
• [EN] COMPOSITIONS AND METHODS RELATED TO CANNABINOID ANIONS<br/>[FR] COMPOSITIONS ET PROCÉDÉS ASSOCIÉS À DES ANIONS CANNABINOÏDES
  申请人：NATURAL EXTRACTION SYS LLC

  公开号：WO2021158714A1

  公开（公告）日：2021-08-12

  Various aspects of the disclosure relate to compositions comprising a liquid phase that comprises a cannabinoid anion, wherein the cannabinoid anion is the conjugate base of a cannabinoid molecule, and the cannabinoid molecule has an acid dissociation constant in water of at least 50 femtomolar and no greater than 50 nanomolar for conversion of the cannabinoid molecule into the cannabinoid anion.