十七碳-8-烯 | 2579-04-6

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 中文名称: 十七碳-8-烯
• 英文名称: heptadec-8-ene
• 英文别名: 8-heptadecane；8-heptadecene；8-heptadecen；C17:1；Heptadec-8-en；λ-Heptadecylen
• CAS: 2579-04-6
• 化学式: C₁₇H₃₄
• 分子量: 238.457
• InChiKey: BIQKRILZMDQPHI-UHFFFAOYSA-N

物化性质

• 熔点：
  -12.5-11.5 °C
• 沸点：
  173 °C(Press: 16 Torr)
• 密度：
  0.795 g/cm3(Temp: 25 °C)
• LogP：
  8.959 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  17
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.882
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险性防范说明：
  P261,P272,P280,P302+P352,P333+P313,P363,P501
• 危险性描述：
  H317

反应信息

• 作为反应物：
  描述：

  十七碳-8-烯 生成 Heptadecan-8,9-diol
  参考文献：
  名称：

  Bashkirov,A.N. et al., Doklady Chemistry, 1969, vol. 184, p. 50 - 51

  摘要：

  DOI：
• 作为产物：
  描述：

  十七烷-9-醇 在 aluminum oxide 作用下， 生成 十七碳-8-烯
  参考文献：
  名称：

  Bashkirov,A.N. et al., Doklady Chemistry, 1969, vol. 184, p. 50 - 51

  摘要：

  DOI：

文献信息

• Reactions en milieu heterogene solide-liquide faiblement hydrate : la reaction de wittig dans le systeme hydroxydes alcalins/solvant organique aprotique
  作者：Yves Le Bigot、Michel Delmas、Antoine Gaset

  DOI：10.1016/s0040-4020(01)85886-5

  日期：1988.1

  The Wittig reaction carried out in a slighty hydrated solid-liquid media constituted by a solid alkaline hydroxyde and an organic phase which includes the phosphonium salt and the aldehyde leads easily to the corresponding alkene with very good yields specially with furanic aldehydes. The ylide formation at the interface appears as the most important step of this condensation.

  在由固体碱性羟基和包括phase盐和醛的有机相组成的略微水合的固液介质中进行的Wittig反应易于以非常好的收率产生相应的烯烃，特别是呋喃醛。界面处的叶立德形成似乎是这种缩合的最重要步骤。
• Factors affecting reactions of trialkylcyanoborates with imidoyl chlorides/trifluoroacetic anhydride
  作者：Dyfyr Heulyn Jones、Keith Smith、Mark C. Elliott、Gamal A. El-Hiti

  DOI：10.1016/j.tet.2015.06.038

  日期：2015.9

  for the synthesis of quaternary carbon centres. Herein we report investigations into generation of tert-alkyl organoboron species using imidoyl chlorides as reagents in the organoboron cyanidation reaction. Although alkenyl side-products predominate in particularly hindered cases, tert-alkyl organoboron species can be successfully generated for less hindered examples.

  产生叔烷基有机硼物质的方法有很高的要求，因为它们是合成季碳中心的宝贵中间体。在此，我们报道了在有机硼氰化反应中使用亚氨酰氯作为试剂对生成叔烷基有机硼物质的研究。尽管在特别受阻碍的情况下，烯基副产物占主导，但是对于受较少阻碍的例子，可以成功地产生叔烷基有机硼物质。
• Non-organic visual loss in children
  作者：Karen E Bain、Stephen Beatty、Chris Lloyd

  DOI：10.1038/eye.2000.201

  日期：2000.9

  Background Patients with non-organic visual loss (NOVL) can take up a disproportionate amount of clinic time and clinicians often resort to expensive and prolonged investigations to ensure the correct diagnosis. This is especially the case in children. Methods The case notes of 30 children (18 girls, 12 boys) were retrospectively reviewed following presentation with a primary complaint of visual impairment and a diagnosis of non-organic visual loss. This figure represents 1% of new paediatric referrals to our unit. Associated symptoms included headache, periorbital pain, diplopia, photopsia and photophobia. Visual field defects were present in 5 patients and spasm of the near reflex in 1 child. Results Treatment consisted of reassurance and was associated with recovery of normal visual function in all cases. Three children were referred to other health care professionals. All psychophysical, electrophysiological and neuroradiological investigations were negative. Conclusion Our study shows that non-organic visual loss is relatively common in pre- pubertal children and that this condition can be safely diagnosed using standard clinical tests in the majority of cases. Prompt diagnosis prevents unnecessary investigations and prolonged 'disease' course. Coexisting social conflict was common and may be a contributory factor. Careful explanation and reassurance to both the child and parents remains the mainstay of management.

  背景 非器质性视力丧失（NOVL）患者会占用大量的门诊时间，临床医生往往需要进行昂贵而漫长的检查以确保诊断正确。儿童的情况尤其如此。方法 回顾性审查了 30 名儿童（18 名女孩，12 名男孩）的病例记录，他们的主诉是视力受损，诊断为非器质性视力损失。这一数字占本单位儿科新转诊病例的 1%。相关症状包括头痛、眶周疼痛、复视、畏光和怕光。5 名患者出现视野缺损，1 名儿童出现近反射痉挛。结果 治疗包括安抚，所有病例的视功能均恢复正常。三名患儿被转诊至其他医疗机构。所有心理物理学、电生理学和神经放射学检查结果均为阴性。结论 我们的研究表明，非器质性视力丧失在青春期前儿童中较为常见，大多数病例可通过标准临床测试安全地诊断出来。及时诊断可避免不必要的检查和延长 "病程"。同时存在的社会冲突很常见，可能也是诱因之一。向患儿和家长仔细解释并安抚他们的情绪仍然是治疗的主要方法。
• Barton decarboxylation under ultrasonic continuous flow
  作者：Estelle Banaszak-Léonard、Floriane Mangin、Christophe Len

  DOI：10.1039/c6nj01368f

  日期：——

  Barton decarboxylation was performed in ultrasonic continuous flow for bulkier syntheses and enhanced yields compared to conventional heating.

  巴顿脱羧反应在超声连续流动条件下进行，与传统加热相比，可实现更大规模的合成和提高产率。
• Determination of oxirane ring position in epoxides at the nanogram level by reaction gas chromatography
  作者：Athula B. Attygalle、E. David. Morgan

  DOI：10.1021/ac00272a074

  日期：1984.7.1