sulfuric acid;(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: sulfuric acid;(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol
• 化学式: C29H52O6S
• 分子量: 528.8
• InChiKey: QDKATGZVZCYPCX-WTCAIEHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.19
• 重原子数：
  36
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] SOLID DISPERSIONS OF LOW-WATER SOLUBILITY ACTIVES<br/>[FR] DISPERSIONS SOLIDES D'AGENTS ACTIFS FAIBLEMENT HYDROSOLUBLES
  申请人：BEND RES INC

  公开号：WO2014126969A1

  公开（公告）日：2014-08-21

  Disclosed are compositions including a solid dispersion comprising a dispersion polymer, a basic low-water solubility active, and an anionic counterion, as well as methods of making and using the compositions.

  揭示了包括固体分散体的组合物，其中包括分散聚合物、一种碱性低水溶性活性物质和一种阴离子对离子的组合物，以及制备和使用这些组合物的方法。
• AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION AND ANTI-AGING COMPOSITION
  申请人：Showa Denko K.K.

  公开号：EP3213739A1

  公开（公告）日：2017-09-06

  Provided is an agent for improving mitochondrial function including a hydroxycitric acid derivative represented by the following Formula (I) or a salt thereof, as an active ingredient [(In Formula (I), R1 and R2 each independently represent a hydrogen atom or any one group selected from the group represented by the following Formula (Ia) (here, R1 and R2 do not represent hydrogen atoms at the same time), X1 to X3 each independently represent a nitrogen or an oxygen atom, and R3, R4, R5, R3', R4', and R5' each independently represent a hydrogen atom, or a chained hydrocarbon group (here, in a case where X1, X2, and X3 each independently represent an oxygen atom, corresponding R3', R4', or R5' does not exist). In Formula (Ia), R6 to R8 each independently represent a hydrogen atom, an aryl group, or a chained hydrocarbon group having 1 to 30 carbon atoms].

  提供了一种改善线粒体功能的制剂，包括由下式(I)代表的羟基柠檬酸衍生物或其盐，作为活性成分[(在式(I)中，R1和R2各自独立地代表氢原子或选自下式(Ia)所代表的基团中的任意一个基团（此处、R1和R2不同时代表氢原子），X1至X3各自独立地代表氮原子或氧原子，R3、R4、R5、R3'、R4'和R5'各自独立地代表氢原子或链状烃基（此处，在X1、X2和X3各自独立地代表氧原子的情况下，不存在相应的R3'、R4'或R5'）。在式 (Ia)中，R6 至 R8 各自独立地代表氢原子、芳基或具有 1 至 30 个碳原子的链状烃基]。
• SKIN BARRIER FUNCTION-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN BARRIER FUNCTION
  申请人：Showa Denko K.K.

  公开号：EP3213753A1

  公开（公告）日：2017-09-06

  The present invention provides a skin barrier function-improving agent including an inositol derivative as an active ingredient in which inositol and saccharide are bonded, and a composition for improving a skin barrier function including the above skin barrier function-improving agent and a pharmacologically acceptable carrier.

  本发明提供了一种皮肤屏障功能改善剂，其中包括一种以肌醇衍生物为活性成分、肌醇和糖键合的皮肤屏障功能改善剂，以及一种用于改善皮肤屏障功能的组合物，其中包括上述皮肤屏障功能改善剂和药理学上可接受的载体。
• MOISTURIZING AGENT
  申请人：Showa Denko K.K.

  公开号：EP3219304A1

  公开（公告）日：2017-09-20

  The present invention provides a moisturizing agent including an inositol derivative as an active ingredient in which saccharide of three or more monosaccharide unit is bonded to per molecule of inositol.

  本发明提供了一种包括肌醇衍生物作为活性成分的保湿剂，其中每个肌醇分子都键合了三个或三个以上单糖单元的糖。
• Solid dispersions of low-water solubility actives
  申请人：Bend Research, Inc.

  公开号：US10322126B2

  公开（公告）日：2019-06-18

  Disclosed are compositions including a solid dispersion comprising a dispersion polymer, a basic low-water solubility active, and an anionic counterion, as well as methods of making and using the compositions.

  本发明公开了包括由分散聚合物、碱性低水溶性活性物质和阴离子反离子组成的固体分散体的组合物，以及组合物的制造和使用方法。