o-methylphenylmethylenemalonic acid | 58818-65-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: o-methylphenylmethylenemalonic acid
• 英文别名: 2-Methylbenzylidenemalonic acid；2-[(2-methylphenyl)methylidene]propanedioic acid
• CAS: 58818-65-8
• 化学式: C₁₁H₁₀O₄
• 分子量: 206.198
• InChiKey: ZXCRUOKKEYFRRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  o-methylphenylmethylenemalonic acid 在 钯 作用下， 以 乙酸乙酯 、 乙醇 为溶剂， 反应 2.0h， 以to obtain the title compound as a beige solid, m.p. 132°-5°的产率得到2-(2-甲基苄基)-丙二酸
  参考文献：
  名称：

  Mercapto-acylamino acid antihypertensives

  摘要：

  本发明揭示了在治疗高血压方面有用的新型巯基-酰基氨基酸，以及用于治疗高血压的巯基-酰基氨基酸和心房利钠肽因子或血管紧张素转换酶抑制剂的组合。

  公开号：

  US04929641A1
• 作为产物：
  描述：

  丙二酸 、 2-甲基苯甲醛 在 aluminum oxide 作用下， 反应 0.12h， 以88%的产率得到o-methylphenylmethylenemalonic acid
  参考文献：
  名称：

  丙二酸在碱性氧化铝上的微波增强 Knoevenagel 缩合

  摘要：

  摘要：通过微波辐射氧化铝可以实现丙二酸和醛的改进的 Knoevenagel 缩合。在很短的反应时间内以良好的收率制备了许多二酸。

  DOI：

  10.1080/00397919708005456

文献信息

• Solvent-free bentonite-catalyzed condensation of malonic acid and aromatic aldehydes under microwave irradiation
  作者：André Loupy、Suk-Jin Song、Sun-Mee Sohn、Young-Mee Lee、Tae-Woo Kwon

  DOI：10.1039/b009803p

  日期：——

  Solvent-free condensation between malonic acid and aromatic aldehydes is studied in the presence of bentonite. Various diacids are prepared in good to moderate yields and in very short reaction times under microwave irradiation.

  研究了在膨润土存在下，丙二酸与芳香醛之间的无溶剂缩合反应。在微波辐射条件下，通过非常短的反应时间制备出了各种二酸，产率从中等到良好不等。
• SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：Uozumi Toshiya

  公开号：US20140221583A1

  公开（公告）日：2014-08-07

  An olefin polymer that is obtained using an olefin polymerization catalyst that includes a solid catalyst component for olefin polymerization that includes titanium, magnesium, a halogen, and an ester compound (A) represented by the following formula (1): R 1 R 2 C═C(COOR 3 )(COOR 4 ), an organoaluminum compound, and an optional external electron donor compound, exhibits primary properties (e.g., molecular weight distribution and stereoregularity) similar to those of an olefin polymer obtained using a solid catalyst component that includes a phthalic ester as an electron donor.

  使用一种包括钛、镁、卤素和酯化合物(A)的固体催化剂组分（式子1：R1R2C═C(COOR3)(COOR4)）进行烯烃聚合得到的烯烃聚合物，加上有机铝化合物和可选的外部电子给体化合物，表现出与包括邻苯二甲酸酯作为电子给体的固体催化剂组分得到的烯烃聚合物相似的主要性质（如分子量分布和立构规则性）。
• METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER
  申请人：Toho Titanium CO., LTD.

  公开号：EP2876118A1

  公开（公告）日：2015-05-27

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds selected from specific aromatic dicarboxylic diesters into contact with each other to effect a reaction, followed by washing, a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing, and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种选自特定芳香族二羧酸二酯的第一内部电子供体化合物相互接触以发生反应，然后进行洗涤、第二步：使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；第三步：使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS
  申请人：TOHO TITANIUM CO., LTD.

  公开号：EP2963063A1

  公开（公告）日：2016-01-06

  A method for producing a solid catalyst component for olefin polymerization produces a novel solid catalyst component for olefin polymerization that achieves excellent olefin polymerization activity and activity with respect to hydrogen during polymerization, and can produce an olefin polymer that exhibits a high MFR, high stereoregularity, and excellent rigidity. The method includes a first step that brings a magnesium compound, a tetravalent titanium halide compound, and one or more first internal electron donor compounds excluding an aromatic dicarboxylic acid diester into contact with each other to effect a reaction, followed by washing; a second step that brings a tetravalent titanium halide compound and one or more second internal electron donor compounds into contact with a product obtained by the first step to effect a reaction, followed by washing; and a third step that brings one or more third internal electron donor compounds into contact with a product obtained by the second step to effect a reaction.

  一种生产烯烃聚合用固体催化剂组分的方法可生产出一种新型的烯烃聚合用固体催化剂组分，该组分具有优异的烯烃聚合活性和聚合过程中对氢的活性，并可生产出具有高MFR、高立体规整度和优异刚性的烯烃聚合物。该方法包括第一步，使镁化合物、四价卤化钛化合物和一种或多种第一内部电子供体化合物（不包括芳香族二羧酸二酯）相互接触以发生反应，然后进行洗涤；第二步，使四价卤化钛化合物和一种或多种第二内部电子供体化合物与第一步得到的产物接触，以发生反应，然后进行洗涤；以及第三步，使一种或多种第三内部电子供体化合物与第二步得到的产物接触，以发生反应。
• Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer
  申请人：TOHO TITANIUM CO., LTD.

  公开号：US11192965B2

  公开（公告）日：2021-12-07

  Provided is a solid catalyst component for olefin polymerization comprising an electron-donating compound other than a phthalate, the solid catalyst component being equal in the olefin-polymerizing activity and in the primary physical properties of the resulting polymer such as stereoregularity and molecular weight distribution to those with use of a phthalate as an electron-donating compound. A solid catalyst component for olefin polymerization comprises a magnesium atom, a titanium atom, a halogen atom, an ester compound (A) represented by a general formula (1) and a diester compound (B) represented by a general formula (2), wherein a ratio represented by the following expression: (content (mass %) of ester compound (A)/content (mass %) of diester compound (B)) is 0.05 to 50.

  本发明提供了一种用于烯烃聚合的固体催化剂组分，该组分包括邻苯二甲酸酯以外的一种电子供体化合物，该固体催化剂组分在烯烃聚合活性和所得聚合物的主要物理性质（如立体规整度和分子量分布）方面与使用邻苯二甲酸酯作为电子供体化合物的催化剂组分相同。用于烯烃聚合的固体催化剂组分包括镁原子、钛原子、卤素原子、通式（1）表示的酯化合物 （A）和通式（2）表示的二酯化合物（B），其中 由以下表达式表示的比例： (酯化合物（A）的含量（质量百分比）/二酯化合物（B）的含量（质量百分比）) 为 0.05 至 50。