6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride | 70509-95-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride
• 英文别名: 6-Methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-on; Hydrochlorid
• CAS: 70509-95-4
• 化学式: C₂₀H₁₉NO₃*ClH
• 分子量: 357.837
• InChiKey: TXWFOBLYBHFJOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.31
• 重原子数：
  25.0
• 可旋转键数：
  1.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  40.46
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  6-methoxy-3,3,12-trimethyl-3,12-dihydro-pyrano[2,3-c]acridin-7-one; hydrochloride 、 乙酸酐 生成 Acetic acid 1-hydroxy-2,10-dimethyl-9-oxo-9,10-dihydro-acridin-3-yl ester
  参考文献：
  名称：

  New Acridone Derivatives Obtained by Heating the HCl Salt of Acronycine

  摘要：

  By heating the HCl salt of acronycine (1), the new acridone derivatives (6, 9, 13 and 15) were obtained together with noracronycine (2), dihydronoracronycine (3), 1,3-dihydroxy-10-methylacridone (4) and (5). Compound (5), one of the main products of this reaction, is a linear type dihydro derivative of 2, compound (9) is a furanoacridone derivative with a geminal methyl group and compound (15) is a derivative of 5 with an additional C-5 unit.

  DOI：

  10.3987/com-96-7442