2,3-dichloro-4,4-dimethoxycyclopent-2-en-1-one | 1156503-07-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3-dichloro-4,4-dimethoxycyclopent-2-en-1-one
• 英文别名: 2,3-Dichloro-4,4-dimethoxycyclopent-2-en-1-one
• CAS: 1156503-07-9
• 化学式: C₇H₈Cl₂O₃
• 分子量: 211.045
• InChiKey: ATABWBSUNARVGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (+/-)-2,3,5-trichloro-4,4-dimethoxycyclopent-2-en-1-one 在 chromium dichloride 作用下， 以 水 、 丙酮 为溶剂， 反应 3.0h， 以96%的产率得到2,3-dichloro-4,4-dimethoxycyclopent-2-en-1-one
  参考文献：
  名称：

  Direct synthesis of 2,3,5-trichloro-4,4-dimethoxy-and 2,5-dichloro-3,4,4-trimethoxycyclopent-2-en-1-ones from hexachlorocyclopentadiene and some aspects of their reactivity

  摘要：

  2,3,5-Trichloro-4,4-dimethoxy-and 2,5-dichloro-3,4,4-trimethoxycyclopent-2-en-1-ones were synthesized directly by treatment of hexachlorocyclopentadiene with methanol in the presence of potassium hydroxide at room temperature or on heating and subsequent acidification of the reaction mixture. Reactions of 2,3,5-trichloro-4,4-dimethoxycyclopent-2-en-1-one with some reducing agents and nucleophiles were studied.

  DOI：

  10.1134/s1070428008090042

文献信息

• Direct synthesis of 2,3,5-trichloro-4,4-dimethoxy-and 2,5-dichloro-3,4,4-trimethoxycyclopent-2-en-1-ones from hexachlorocyclopentadiene and some aspects of their reactivity
  作者：N. A. Ivanova、K. S. Kislitsina、M. S. Miftakhov

  DOI：10.1134/s1070428008090042

  日期：2008.9

  2,3,5-Trichloro-4,4-dimethoxy-and 2,5-dichloro-3,4,4-trimethoxycyclopent-2-en-1-ones were synthesized directly by treatment of hexachlorocyclopentadiene with methanol in the presence of potassium hydroxide at room temperature or on heating and subsequent acidification of the reaction mixture. Reactions of 2,3,5-trichloro-4,4-dimethoxycyclopent-2-en-1-one with some reducing agents and nucleophiles were studied.