[2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-phenyl]-acetic acid | 178118-35-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-phenyl]-acetic acid
• 英文别名: 2-[(4,6-Dimethoxy-2-pyrimidinyl)oxy]benzeneacetic acid；2-[2-(4,6-dimethoxypyrimidin-2-yl)oxyphenyl]acetic acid
• CAS: 178118-35-9
• 化学式: C₁₄H₁₄N₂O₅
• 分子量: 290.276
• InChiKey: VQHQKCCLYUVSSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  90.8
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  4,6-二甲氧基-2-甲硫基嘧啶 在 sodium hydroxide 、 sodium tungstate 、 双氧水 、 potassium carbonate 作用下， 以 甲醇 、 溶剂黄146 、 丁酮 为溶剂， 反应 3.0h， 生成 [2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-phenyl]-acetic acid
  参考文献：
  名称：

  Dimethoxypyrimidines as Novel Herbicides. Part 2. Synthesis and Herbicidal Activity ofO-Pyrimidinylsalicylates and Analogues

  摘要：

  A new series of the O-pyrimidinylsalicylates was synthesized and their herbicidal activity was examined. Some of these compounds showed very strong herbicidal activity under pre- and post-emergent treatment conditions against various kinds of grass and broadleaf weeds. Among these compounds, O-(4, 6-dimethoxypyrimidin-2-yl) salicylic acid and its methyl ester were found to exhibit the highest activity. The herbicidal symptoms observed after the treatments included early cessation of plant growth followed by chlorosis, necrosis and plant death. The symptoms were similar to those caused by sulfonylureas and imidazolinones, which inhibit branched-chain amino acid biosynthesis.

  DOI：

  10.1002/(sici)1096-9063(199606)47:2<115::aid-ps397>3.0.co;2-r

文献信息

• JPH01301668A
  申请人：——

  公开号：JPH01301668A

  公开（公告）日：1989-12-05