4-[4-(sulfanylmethyl)phenyl]pentan-2-yloxymethanethioic S-acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 4-[4-(sulfanylmethyl)phenyl]pentan-2-yloxymethanethioic S-acid
• 化学式: C₁₃H₁₈O₂S₂
• 分子量: 270.4
• InChiKey: NNLMICCLPSCQNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  28.3
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• PREPARATION PROCESS OF PSMA BINDING LIGAND-LINKER CONJUGATES
  申请人：Purdue Research Foundation

  公开号：EP3656403A1

  公开（公告）日：2020-05-27

  Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

  本文描述的是前列腺特异性膜抗原（PSMA）结合共轭物，可用于递送治疗、诊断和成像制剂。本文还描述了含有它们的药物组合物以及使用这些共轭物和组合物的方法。还描述了共轭物和含有共轭物的组合物的制造工艺。
• Cholecystokinin B receptor targeting for imaging and therapy
  申请人：Purdue Research Foundation

  公开号：US10765756B2

  公开（公告）日：2020-09-08

  Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.

  本文描述了 CCK2R 靶向配体通过连接体连接到活性分子（如治疗剂或成像剂）上的共轭物。这些共轭物可用于癌症的检测、诊断、成像和治疗。