2,3-dimethoxy-5-methyl-6-[(E)-3-methylpent-2-enyl]benzene-1,4-diol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2,3-dimethoxy-5-methyl-6-[(E)-3-methylpent-2-enyl]benzene-1,4-diol
• 化学式: C₁₅H₂₂O₄
• 分子量: 266.33
• InChiKey: BCZFYNGGRBVBAW-VQHVLOKHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• New Drug Delivery System for Crossing the Blood Brain Barrier
  申请人：Lipshutz H. Bruce

  公开号：US20070203080A1

  公开（公告）日：2007-08-30

  New ubiquinol analogs are disclosed, as well as methods of using these compounds to deliver drug moieties to the body.

  新的泛醌类似物被披露，以及利用这些化合物将药物基团输送到人体的方法。
• PQS: A NEW HYDROTROPE FOR SOLUBILIZING LIPOPHILIC COMPOUNDS IN WATER
  申请人：Lipshutz H. Bruce

  公开号：US20070208088A1

  公开（公告）日：2007-09-06

  The present invention provides a solubilizing agent of the general formula: wherein R 11 , R 12 and R 13 are members independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl. L1 and L2 are linker moieties, which are members independently selected from substituted or unsubstituted alkyl and substituted or unsubstituted heteroalkyl. Y1 and Y2 are hydrophilic moieties, which are members independently selected from polyethers, polyalcohols and derivatives thereof. Z1, Z2, Z3 and Z4 are members independently selected from 0 and 1, wherein at least one of Z1 and Z2 is 1.

  本发明提供了一种通式为的溶解剂剂：其中，R11、R12和R13分别是H、取代或未取代的烷基、取代或未取代的杂烷基、取代或未取代的环烷基、取代或未取代的杂环烷基、取代或未取代的芳基和取代或未取代的杂芳基中的独立成员。L1和L2是连接基，分别是取代或未取代的烷基和取代或未取代的杂烷基中的独立成员。Y1和Y2是亲水性基团，分别是聚醚、多元醇及其衍生物中的独立成员。Z1、Z2、Z3和Z4是独立选择的成员0和1，其中至少一个Z1和Z2为1。
• UBIQUINONE ANALOGS AND METHODS OF USE
  申请人：Lipshutz H. Bruce

  公开号：US20070208086A1

  公开（公告）日：2007-09-06

  New ubiquinone and ubiquinol analogs are disclosed, as well as methods of making and using these compounds.

  本发明揭示了新的泛醌和泛醌醇类似物，以及制备和使用这些化合物的方法。