Epiduo | 1194805-81-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Epiduo
• 英文别名: 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid;benzoyl benzenecarboperoxoate
• CAS: 1194805-81-6
• 化学式: C42H38O7
• 分子量: 654.7
• InChiKey: UXWMHYHGBDEQJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  49
• 可旋转键数：
  9
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  99.1
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Combination/association of adapalene and benzoyl peroxide for treating acne lesions
  申请人：Chacra Vernet Abou Marie-Line

  公开号：US20080033047A1

  公开（公告）日：2008-02-07

  Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
• Combinations of adapalene and benzoyl peroxide for treating acne lesions
  申请人：Vernet Marie-line Abou-Chacra

  公开号：US20090253788A1

  公开（公告）日：2009-10-08

  Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
• COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
  申请人：Abou-Chacra Vernet Marie-line

  公开号：US20090298798A1

  公开（公告）日：2009-12-03

  Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
• COMBINATION/ASSOCIATION OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
  申请人：Chacra Vernet Marie-Line Abou

  公开号：US20120115947A1

  公开（公告）日：2012-05-10

  Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
• COMBINATION/ASSOCIATION OF ADAPALENE AND BENXOYL PEROXIDE FOR TREATING ACNE LESIONS
  申请人：GALDERMA RESERCH & DEVELOPMENT

  公开号：US20140296340A1

  公开（公告）日：2014-10-02

  Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).