三乙醇胺硼酸盐 | 15277-97-1

• 物质功能分类: 化学试剂 - 有机试剂 - 硼酸酯
• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 中文名称: 三乙醇胺硼酸盐
• 中文别名: 三乙醇胺硼酸酯；2,2',2''-三乙醇胺硼酸盐；硼酸三乙醇胺
• 英文名称: 1-aza-4,6,11-trioxa-5-boratricyclo[3.3.3.0(1,5)]undecane
• 英文别名: boraza trioxo[3.3.3]propellane；triethanolamine borate；borathrene；boratrane；borotrane；2,8,9-Trioxa-5-azonia-1-boranuidatricyclo[3.3.3.01,5]undecane
• CAS: 15277-97-1
• 化学式: C₆H₁₂BNO₃
• 分子量: 156.977
• InChiKey: GMYXIZZESUQGPX-UHFFFAOYSA-N

物化性质

• 熔点：
  235-237 °C(lit.)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.67
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• TSCA：
  No
• 危险品标志：
  Xi
• 安全说明：
  S26,S36/37
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• RTECS号：
  YJ8968050
• 储存条件：
  存储于室温下。

SDS

Name:	Triethanolamine borate 95+% (ex nitrogen) Material Safety Data Sheet
Synonym:	2,2',2''-Nitriloethylborat
CAS:	15277-97-1

Section 1 - Chemical Product MSDS Name:Triethanolamine borate 95+% (ex nitrogen) Material Safety Data Sheet
Synonym:2,2',2''-Nitriloethylborat

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
15277-97-1	Triethanolamine borate	97.0	239-317-6

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.Moisture sensitive.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Not available.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Antidote: None reported.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Can burn in a fire, releasing toxic vapors.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Use with adequate ventilation.
Storage:
Store in a tightly closed container. Keep under a nitrogen blanket.
Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 15277-97-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 235 - 237 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water: slightly soluble in acetone, benzene and
Specific Gravity/Density:
Molecular Formula: C6H12NO3B
Molecular Weight: 156.99

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, moist air or water.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, oxides of boron.
Hazardous Polymerization: Will not occur.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 15277-97-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Triethanolamine borate - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION
Other No information available.

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 15277-97-1: No information available.
Canada
CAS# 15277-97-1 is listed on Canada's NDSL List.
CAS# 15277-97-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 15277-97-1 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

制备方法

具有防锈、润滑和乳化作用，它是切削液、防锈剂和乳化液的理想添加剂。

用途简介

暂无具体用途介绍。

反应信息

• 作为反应物：
  描述：

  三乙醇胺硼酸盐 在 aluminum (III) chloride 、 三乙氧基硅烷 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 为溶剂， 反应 4.0h， 以88%的产率得到1-hydrosilatrane
  参考文献：
  名称：

  COMPOSITIONS AND METHODS FOR REDUCTION OF KETONES, ALDEHYDES AND IMINIUMS, AND PRODUCTS PRODUCED THEREBY

  摘要：

  生产醇的方法包括使用氢硅氮烷还原醛或酮。还原过程中需要使用活化剂。

  公开号：

  US20170362151A1
• 作为产物：
  描述：

  三乙醇胺 、 硼酸 以 氘代氯仿 为溶剂， 生成 三乙醇胺硼酸盐
  参考文献：
  名称：

  硼酸与三乙醇胺在水溶液中的络合物形成

  摘要：

  硼酸和三乙醇胺（TEA，H3L）在水溶液中的络合物形成行为通过 11B NMR 光谱学进行了彻底检查。在氯仿中，由于三乙醇胺硼酸盐（TEA-B，LB）在 -4.6 ppm 处出现了一个 11B NMR 信号，而在水溶液中，由于 TEA-B 和一种新的硼络合物在 -5.8 和 -9.5 ppm 处出现了两个信号，除了归因于硼酸和硼酸盐离子的信号。无论硼酸和 TEA 之间的摩尔比如何，-5.8 和 -9.5 ppm 信号之间的面积比几乎是恒定的，这表明新复合物是硼酸和 TEA 之间的 1:1 复合物。在 6.7 至 10.9 的 pH 值范围内，两种复合物在水溶液中都是稳定的。它们的化学位移值是恒定的并且与 pH 值无关。这也意味着新配合物在硼原子周围具有四面体结构，类似于 TEA-B。基于 1H 和 13C NMR 光谱以及硼酸与...

  DOI：

  10.1246/bcsj.71.161
• 作为试剂：
  描述：

  苯并噻唑 、 对溴甲苯 在 二(氰基苯)二氯化钯 、 1,10-菲罗啉 、 三乙醇胺硼酸盐 、 二异丙胺 作用下， 以 水 、 二甲基亚砜 、 正丁醇 为溶剂， 反应 10.0h， 以95.1%的产率得到2-(4-甲基苯基)苯并噻唑
  参考文献：
  名称：

  一种医药中间体2-芳基苯并噻唑类化合物的 合成方法

  摘要：

  本发明涉及一种下式(III)所示的2‑芳基苯并噻唑类化合物的合成方法，所述方法包括：在三组分复合溶剂中，于催化剂、碱和促进剂存在下，下式(I)化合物与下式(II)化合物进行反应，从而得到所述式(III)化合物，其中，R1、R2各自独立地选自H、C1‑C6烷基、C1‑C6烷氧基、卤素或硝基；X为卤素。所述方法通过催化剂、碱、促进剂和三组分溶剂体系的选择、组合，从而发挥了独特的协同作用，取得了优良的产物产率，在医药领域具有工业化应用的实际价值。

  公开号：

  CN105037294B

文献信息

• Organoboranes
  作者：Herbert C. Brown、Milind V. Rangaishenvi

  DOI：10.1016/0022-328x(88)87067-0

  日期：1988.12

  Matteson's asymmetric synthesis via a one-carbon homologation of the pinanediol boronic esters with (dichloromethyl)lithium at −100°C results in the insertion of a chloromethyl group into the carboncarbon bond with > 99% diastereoselectivity. This procedure makes possible the asymmetric synthesis of the chiral moiety, RR′CH★B(OR″)2, providing an alternative route to chiral hydroboration for these

  Matteson的不对称合成是在-100°C下通过the烷二醇硼酸酯与（二氯甲基）锂的一碳同系物导致的，氯甲基以> 99％的非对映选择性插入到碳碳键中。该方法使得手性部分RR'CH ★ B（OR''）2的不对称合成成为可能，从而为这些有价值的手性中间体提供了另一种手性氢硼化的途径。不幸的是，该方法遭受了在the烷二醇手性助剂的回收中遇到的显着困难，使得这种不对称合成是不切实际的。幸运的是，对该问题的系统研究发现了从pin烷二醇硼酸酯中回收pin烷二醇的简便方法。
• Boratrane method of silatrane synthesis
  作者：E. A. Grebneva、A. I. Albanov、O. M. Trofimova、M. G. Voronkov

  DOI：10.1134/s1070363211010257

  日期：2011.1
• A novel route to pentacoordinated organylsilanes and -germanes
  作者：Vladimir Gevorgyan、Larisa Borisova、Armand Vyater、Victoria Ryabova、Edmunds Lukevics

  DOI：10.1016/s0022-328x(97)00454-3

  日期：1997.12

  New convenient methods of sila- and germatranes synthesis from ethoxy-and tetraorganylsilanes and -germanes have been elaborated. The reaction of ethoxysilanes with boratrane in the presence of catalytic amounts of metal alcoholates has been investigated. Dimethylformamide (DMF) as a solvent and NaOEt as a catalyst used instead of xylene and Al(O-i-Pr)(3) were found to give better yields. The possibility of using alkoxy-, aminosilanes, tetraethoxygermane and even tetraorganylsilanes in this reaction leading to the corresponding atranes with good yields has been demonstrated. Triethanolamine in the presence of catalytic amounts of base or CsF easily substitutes furyl-, dihydrofuryl-, dihydropyranyl- and thienyl groups in tris-and tetraheterylsilanes, leading to organylsilatranes with good to excellent yields. (C) 1997 Elsevier Science S.A.
• Ferrocenylethenylsilatranes and a cymantrenylsilatrane
  作者：Bjørn Pedersen、Gabriele Wagner、Rudolf Herrmann、Wolfgang Scherer、Klaus Meerholz、Elmar Schmälzlin、Christoph Bräuchle

  DOI：10.1016/s0022-328x(99)00440-4

  日期：1999.11

  The syntheses, properties and crystal structures of two isomeric ferrocenylethenylsilatranes and 1-(3-methylcymantrenyl)silatrane are reported. The organometallic moieties and the silatrane show little structural influence on each other. The Si-N distances remain in the expected range of 2.13-2.22 Angstrom, asserting the hypervalency of silicon. The electron-donating effect of the silatrane group is transmitted through the C-C double bond to ferrocene, as shown by the redox potentials. The first hyperpolarizability of the ferrocene derivatives was determined by hyper-Rayleigh scattering. (C) 1999 Elsevier Science S.A. All rights reserved.
• COMPOSITIONS AND METHODS FOR REDUCTION OF KETONES, ALDEHYDES AND IMINIUMS, AND PRODUCTS PRODUCED THEREBY
  申请人：Adler Marc J.

  公开号：US20170362151A1

  公开（公告）日：2017-12-21

  A method of producing an alcohol, comprises reducing an aldehyde or a ketone with a hydridosilatrane. The reducing is carried out with an activator.

  生产醇的方法包括使用氢硅氮烷还原醛或酮。还原过程中需要使用活化剂。

表征谱图