1,8-dihydroxy-(+)-neomenthol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1,8-dihydroxy-(+)-neomenthol
• 英文别名: (1S,3S,4R)-4-(2-hydroxypropan-2-yl)-1-methylcyclohexane-1,3-diol
• 化学式: C₁₀H₂₀O₃
• 分子量: 188.267
• InChiKey: JRNAYJOJYCECDH-WEDXCCLWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (1Alpha,2Alpha,5β)-(+-)-5-甲基 以97 mg的产率得到9-hydroxy-(+)-neomenthol
  参考文献：
  名称：

  Biotransformation of (−)- and (+)-neomenthols and isomenthol by Aspergillus niger

  摘要：

  Three menthols, (+)- and(-)-neomenthols and(+)-isomenthol were biotransformed by Aspergillus niger which converted nonspecifically (-)- and (+)-neomenthols to mere hydroxylated compounds, whereas, (+)-isomenthol was smoothly converted into 1-hydroxyisomenthol and 6-hydroxyisomenthol by the same fungus.

  DOI：

  10.1016/s0031-9422(00)86876-4

文献信息

• Biotransformation of (−)- and (+)-neomenthols and isomenthol by Aspergillus niger
  作者：Hironobu Takahashi、Yoshiaki Noma、Masao Toyota、Yoshinori Asakawa

  DOI：10.1016/s0031-9422(00)86876-4

  日期：1994.4.19

  Three menthols, (+)- and(-)-neomenthols and(+)-isomenthol were biotransformed by Aspergillus niger which converted nonspecifically (-)- and (+)-neomenthols to mere hydroxylated compounds, whereas, (+)-isomenthol was smoothly converted into 1-hydroxyisomenthol and 6-hydroxyisomenthol by the same fungus.