5-(((2-aminoethyl) amino) methyl) quinolin-8-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-(((2-aminoethyl) amino) methyl) quinolin-8-ol
• 英文别名: 5-[(2-Aminoethyl)amino]methylquinolin-8-ol；5-[(2-aminoethylamino)methyl]quinolin-8-ol
• 化学式: C₁₂H₁₅N₃O
• 分子量: 217.271
• InChiKey: HKJCUDGUDRNQBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  71.2
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  8-羟基喹啉 在 盐酸 、 碳酸氢钠 作用下， 以 四氢呋喃 为溶剂， 反应 32.0h， 生成 5-(((2-aminoethyl) amino) methyl) quinolin-8-ol
  参考文献：
  名称：

  Synthesis, characterization and bioactivity of novel 8-hydroxyquinoline derivatives: Experimental, molecular docking, DFT and POM analyses

  摘要：

  DOI：

  10.1016/j.molstruc.2022.132688

文献信息

• Design and Synthesis of Nanosensor Based on CdSe Quantum Dots Functionalized with 8-Hydroxyquinoline: a Fluorescent Sensor for Detection of Al3+ in Aqueous Solution
  作者：Bagher Eftekhari-Sis、Khadijeh Samadneshan、Saleh Vahdati-Khajeh

  DOI：10.1007/s10895-018-2238-z

  日期：2018.5

  A novel nanosensor based on CdSe quantum dots (QDs) capped with 8-hydroxyqunoline (HQ) was developed for Al3+ ions determination in aqueous solutions. The method is based on the fluorescence enhancement of the HQ functionalized QDs in the presence of Al3+ ions, due to the strong interaction between Al3+ and HQ. Prepared nanosensor exhibited an acceptable selectivity and sensitivity for Al3+ ions in

  开发了一种新型的基于CdSe量子点（QDs）的纳米传感器，该量子点被8-羟基喹啉（HQ）覆盖，用于测定水溶液中的Al 3+离子。该方法是基于HQ的荧光增强官能化在Al的存在的QD 3+离子时，由于与Al之间的强相互作用3+和HQ。制备的纳米传感器在存在其他金属离子的情况下对Al 3+离子表现出可接受的选择性和灵敏度。Log（I / I 0）对Log [Al 3+ ]的图在0.02–3.0 mM范围内显示出良好的线性，该方法可用于检测水溶液中的Al 3+离子浓度。
• CHELATING MONOMERS AND POLYMERS
  申请人：Zhang Hongmin

  公开号：US20070254378A1

  公开（公告）日：2007-11-01

  This invention provides chelating moieties that comprise an aryl group. Monomers that include the chelating moieties can be polymerized into chelating polymers. Chelating polymers are useful to chelate metals. Chelating polymers in the form of metal chelates are useful for binding analytes, such as polypeptides that comprise histidine residues. Chelating polymers can be includes in articles such as chips and chromatographic materials.

  本发明提供了包含芳基的螯合基团。包括螯合基团的单体可以聚合成螯合聚合物。螯合聚合物可用于螯合金属。以金属螯合物形式的螯合聚合物可用于结合分析物，例如包含组氨酸残基的多肽。螯合聚合物可以包含在芯片和色谱材料等物品中。
• Sample synthesis, characterization, experimental and theoretical study of the inhibitory power of new 8-hydroxyquinoline derivatives for mild steel in 1.0 M HCl
  作者：M. Rbaa、F. Benhiba、Ashraf S. Abousalem、M. Galai、Z. Rouifi、H. Oudda、B. Lakhrissi、I. Warad、A. Zarrouk

  DOI：10.1016/j.molstruc.2020.128155

  日期：2020.8

  Some new compounds which are derived from 8-hydroxyquinoline were both prepared and characterized by IR, NMR spectroscopy and elemental analysis. After the successful synthesis, we tested these products as corrosion inhibitors of mild steel (MS) in 1.0 M HCl at 298 K +/- 1. The anticorrosive property was achieved by electrochemical and theoretical methods such as potentiodynamic polarization (PDP), the spectroscopy impedance (EIS), density functional theory (DFT) calculations and the Monte Carlo simulation (MC). The experimental and theoretical results obtained show that these products have an excellent anticorrosive property for the MS. The thermodynamic parameters show that all the compounds adsorb to the metal surface by chemical bonds according to the Langmuir adsorption isotherm. The surface morphology was investigated using scanning electron spectroscopy (SEM) coupled with energy dispersive spectroscopy (EDS) and the FT-IR analysis. The gravimetric solutions after 6 h of immersion were analyzed by the UV-Visible spectrometry. (c) 2020 Elsevier B.V. All rights reserved.
• [EN] CHELATING MONOMERS AND POLYMERS<br/>[FR] CHÉLATION DE MONOMÈRES ET DE POLYMÈRES
  申请人：BIO RAD LABORATORIES

  公开号：WO2007120999A2

  公开（公告）日：2007-10-25

  [EN] This invention provides chelating moieties that comprise an aryl group. Monomers that include the chelating moieties can be polymerized into chelating polymers. Chelating polymers are useful to chelate metals. Chelating polymers in the form of metal chelates are useful for binding analytes, such as polypeptides that comprise histidine residues. Chelating polymers can be includes in articles such as chips and chromatographic materials.
  [FR] L'invention porte sur la chélation de fragments pouvant comprendre un groupe aryle, les monomères comportant les fragments chélatés pouvant être polymérisés pour donner des polymères chélateurs utiles pour la chélation de métaux. Les polymères chélateurs sous forme de chélats métalliques servent à lier des analytes tels que des polypeptides comprenant des résidus d'histidine. Les polymères chélateurs peuvent comprendre des articles tels que des puces ou des matériaux chromatographiques.
• Synthesis, characterization and bioactivity of novel 8-hydroxyquinoline derivatives: Experimental, molecular docking, DFT and POM analyses
  作者：Mohamed Rbaa、Sara Haida、Burak Tuzun、Abdelhadi hichar、Anouar El Hassane、Abderahim Kribii、Younes Lakhrissi、Taibi Ben Hadda、Abdelkader Zarrouk、Brahim Lakhrissi、Elyor Berdimurodov

  DOI：10.1016/j.molstruc.2022.132688

  日期：2022.6