(Z)-(1R,4S)-menthyl oxime

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-(1R,4S)-menthyl oxime
• 英文别名: (-)-menthone oxime；menthone oxime；(NZ)-N-[(2S,5R)-5-methyl-2-propan-2-ylcyclohexylidene]hydroxylamine
• 化学式: C₁₀H₁₉NO
• 分子量: 169.267
• InChiKey: XJKYDNDJFRDNHX-DUXYUNCLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  lithium tetrachloropalladate 、 (Z)-(1R,4S)-menthyl oxime 以 甲醇 为溶剂， 以83%的产率得到
  参考文献：
  名称：

  Chiral palladium complexes with monoterpenoids oximes

  摘要：

  Oximes of cis-caran-4-one, 3 alpha- and 3 beta-hydroxycaran-4-ones, cis-verbanone, menthone, and 2 beta-hydroxybornan-3-one have been synthesized. The obtained oximes react with lithium tetrachloropalladate to give new chiral palladium complexes containing mono-or bidentate oxime ligands.

  DOI：

  10.1134/s1070363214010216
• 作为产物：
  描述：

  (-)-薄荷酮 在 盐酸羟胺 、 碳酸氢钠 作用下， 以 乙醇 为溶剂， 生成 (-)-(E)-(1R,4S)-menthyl oxime 、 (Z)-(1R,4S)-menthyl oxime
  参考文献：
  名称：

  薄荷酮肟的O-烷基化：一系列新型肟醚的合成和13C NMR研究

  摘要：

  以 (-)-薄荷醇为原料，分三步合成了一系列新型薄荷酮肟醚。对肟衍生物（O-烷基肟）的 α 碳之间的 13C NMR 化学位移差异的分析提供了一种方便可靠的方法来指定肟立体化学。已经发现，与肟部分同性的碳比与肟部分相反的碳更上场移动。获得了显着的E产物。

  DOI：

  10.1080/00397910903370691

文献信息

• Synthesis and Characterization of Enantiomerically Pure Menthylamines and Their Isocyanates
  作者：Siegfried R. Waldvogel、Matthias C. Schopohl、Klaus Bergander、Olga Kataeva、Roland Fröhlich

  DOI：10.1055/s-2003-42432

  日期：——

  A synthetic protocol for optically pure (-)-menthyl­amine, (-)-8-methylmenthylamine, and the novel (-)-8-phenylmenthylamine is presented including a detailed characterization of these compounds and their isocyanates.

  提供了一种光学纯的（-）-薄荷胺、（-）-8-甲基薄荷胺以及新型（-）-8-苯基薄荷胺的合成方案，包括对这些化合物及其异氰酸酯的详细表征。
• <i>O</i>-Alkylation of Menthone Oxime: Synthesis and ¹³C NMR Studies of a Series of Novel Oxime Ethers
  作者：Saqib Faisal、Amina F. Basha、Hina Siddiqui、Fatima Z. Basha

  DOI：10.1080/00397910903370691

  日期：2010.9.20

  menthone oxime ethers were synthesized in three steps starting from (–)-menthol. Analysis of the 13C NMR chemical shift differences between α carbons of oxime derivatives (O-alkyl oximes) provides a convenient and reliable means of assigning oxime stereochemistry. It has been found that carbons syn to the oxime are shifted more upfield than carbons anti to the oxime moiety. Significant E products were

  以 (-)-薄荷醇为原料，分三步合成了一系列新型薄荷酮肟醚。对肟衍生物（O-烷基肟）的 α 碳之间的 13C NMR 化学位移差异的分析提供了一种方便可靠的方法来指定肟立体化学。已经发现，与肟部分同性的碳比与肟部分相反的碳更上场移动。获得了显着的E产物。
• Density balanced high impact perfume microcapsules
  申请人：FIRMENICH SA

  公开号：US10918579B2

  公开（公告）日：2021-02-16

  Described herein are microcapsules having an oil-based core and a polymeric shell, where the oil-based core includes a perfume oil having high impact perfume raw materials and a density balancing material. Perfuming compositions and consumer products including said microcapsules, in particular isotropic or structured consumer products in the form of home care or personal care products, are also described herein.

  本文描述了具有油基核心和聚合物外壳的微胶囊，其中油基核心包括具有高影响香水原料的香水油和密度平衡材料。 本文还描述了包括所述微胶囊的香水组合物和消费品，特别是家庭护理或个人护理产品形式的各向同性或结构化消费品。
• [EN] PROCESS FOR PREPARING POLYESTER MICROCAPSULES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE MICROCAPSULES DE POLYESTER
  申请人：[en]FIRMENICH SA

  公开号：WO2022136008A1

  公开（公告）日：2022-06-30

  The present invention relates to a new process for the preparation of polyester microcapsules. Microcapsules are also an object of the invention. Consumer products comprising said microcapsules, in particular perfumed consumer products or flavoured consumer products are also part of the invention.
• [EN] PROCESS FOR PREPARING MICROCAPSULES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE MICROCAPSULES
  申请人：[en]FIRMENICH SA

  公开号：WO2022136021A1

  公开（公告）日：2022-06-30

  The present invention relates to a new process for the preparation of core-shell microcapsules. Microcapsules are also an object of the invention. Consumer products comprising said microcapsules, in particular perfumed consumer products or flavoured consumer products are also part of the invention.