乳清酸钙 | 22454-86-0

• 物质功能分类: 原料药 - 维生素类与矿物质类药 - 微量元素与矿物质类药
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 乳清酸钙
• CAS: 22454-86-0
• 化学式: C5H4CaN2O4
• 分子量: 196.17
• InChiKey: OEZNXSZTYLOCHG-UHFFFAOYSA-N

物化性质

• 熔点：
  197-199°C
• 溶解度：
  碱性溶液（微溶），DMSO（微溶）
• LogP：
  -0.928 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.62
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  95.5
• 氢给体数：
  3
• 氢受体数：
  4

安全信息

• 海关编码：
  2933599090

文献信息

• Process for preparing a creatine heterocyclic acid salt and method of use.
  申请人：——

  公开号：US20040198823A1

  公开（公告）日：2004-10-07

  This invention relates to a process for the synthesis and method of use of an effective amount of a creatine heterocyclic acid salt for the regulation athletic function in humans.

  这项发明涉及一种用于合成和使用一种有效量的肌酸杂环酸盐的方法，用于调节人类的运动功能。
• Dietary supplements containing iron and enterically coated calcium
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0208362A1

  公开（公告）日：1987-01-14

  A dietary calcium and iron supplement is disclosed. This supplement comprises nutritional amounts of both calcium and iron. The supplement also includes an enteric or like delayed release coating which surrounds the calcium. The enteric coating substantially prevents the calcium from inhibiting the biological absorption of the iron. As a result, calcium and iron can be simultaneously without adverse mineral interactions.

  本发明公开了一种钙铁膳食补充剂。 这种补充剂包括营养含量的钙和铁。 这种补充剂还包括一种肠溶或类似的缓释涂层，这种涂层将钙包裹起来。 肠溶涂层基本上可以防止钙抑制铁的生物吸收。 因此，钙和铁可以同时摄入，而不会产生不利的矿物质相互作用。
• A beverage and method for making a beverage for the nutritional supplementation of calcium in humans
  申请人：Clark, George H.

  公开号：EP0246177A2

  公开（公告）日：1987-11-19

  A beverage comprising a beverage solution containing per 354 ml.: 0.5-50.0 meq. of calcium ions, 0.5-50.0 meq. of magnesium ion, and 1.0-10.0 meq. of potassium ion, sweetener agent; and a stabilizer; provided that each of calcium, magnesium, and potassium ions is in the form of a salt selected from the group consisting of aspartate, orotate, ascorbate, and mixtures thereof. A method for preparing or making the beverages. A method for accelerating the reduction of blood alcohol in the blood stream of a human body into an inactive form. A method for supplying a rapidly and highly absorbable source of calcium to the human body. A method for reducing blood pressure in a human body while not causing any gastric upset and stomach bloating.

  一种饮料，包括一种饮料溶液，每 354 毫升含有：0.5-50.0 meq.的钙离子、0.5-50.0 meq.的镁离子和 1.0-10.0 meq.的钾离子、甜味剂和稳定剂；条件是钙、镁和钾离子中的每一种都是以盐的形式存在，这种盐选自由天门冬氨酸盐、乳清酸盐、抗坏血酸盐及其混合物组成的组。 一种准备或制造饮料的方法。 一种加速将人体血流中的血液酒精还原成非活性形式的方法。 一种向人体提供快速和高度可吸收的钙源的方法。 一种降低人体血压，同时不引起任何胃部不适和胃胀的方法。
• Vitamin and mineral supplements
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0397232A1

  公开（公告）日：1990-11-14

  Vitamin and mineral-fortified beverages, especially carbonated beverages are disclosed. These beverages are stable and contain vitamin A in the form of encapsulated β-carotene, vitamin C and riboflavin. The beverages show enhanced calcium and iron absorption.

  本发明公开了维生素和矿物质强化饮料，特别是碳酸饮料。这些饮料性质稳定，含有封装成 β-胡萝卜素形式的维生素 A、维生素 C 和核黄素。这些饮料还能促进钙和铁的吸收。
• Recombinant IL-9 antibodies & uses thereof
  申请人：MedImmune, LLC

  公开号：EP2316487A1

  公开（公告）日：2011-05-04

  The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide.

  本发明提供了与 IL-9 多肽免疫特异性结合的新型抗体以及包含所述抗体的组合物。本发明还提供了预防、治疗、控制和/或改善与 IL 9 或 IL-9 受体或其亚基的异常表达和/或活性、自身免疫性疾病、炎症性疾病、增殖性疾病和感染相关的疾病和紊乱的方法和组合物，包括施用一种或多种免疫特异性结合 IL-9 多肽的抗体。本发明还包括用于诊断、监测和预后这些疾病的方法和组合物。本发明还涉及包含免疫特异性结合 IL-9 多肽的抗体的制成品和试剂盒。