2,4,6-tri(2-methoxycarbonylphenoxy)-1,3,5-triazine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4,6-tri(2-methoxycarbonylphenoxy)-1,3,5-triazine
• 英文别名: Methyl 2-[[4,6-bis(2-methoxycarbonylphenoxy)-1,3,5-triazin-2-yl]oxy]benzoate
• 化学式: C₂₇H₂₁N₃O₉
• 分子量: 531.478
• InChiKey: PZFZPZSRBCOVSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  39
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  145
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  2,4,6-tri(2-methoxycarbonylphenoxy)-1,3,5-triazine 在 palladium 10% on activated carbon 、 氢气 作用下， 以 乙酸乙酯 为溶剂， 反应 24.0h， 以10%的产率得到苯甲酸甲酯
  参考文献：
  名称：

  A Mild and Selective Method for the Catalytic Hydrodeoxygenation of Cyanurate Activated Phenols in Multiphasic Continuous Flow

  摘要：

  sA low-energy, high-selectivity approach to the catalytic hydrodeoxygenation of phenols is reported using batch or continuous flow methods to react 3 equiv of phenol with cyanuric chloride then hydrogenolyzing the triarylcyanurate intermediate to give 3 equiv of deoxo aromatic. The use of cyanuric chloride compares favorably with existing activation methods, showing improved scalability, atom efficiency, and economics. The scope of both the activation and hydrogenolysis stages are explored using lignin-related phenols. Initial development has identified that continuous stir tank reactors (CSTRs) enable a multiphasic process for converting guaiacol to anisole and at steady state overcome the catalyst deactivation issues observed in batch, seemingly caused by the cyanurate byproduct. Green chemistry aspects and the potential for industrial adoption are discussed.

  DOI：

  10.1021/acs.oprd.6b00314
• 作为产物：
  描述：

  三聚氯氰 、 水杨酸甲酯 在 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以66%的产率得到2,4,6-tri(2-methoxycarbonylphenoxy)-1,3,5-triazine
  参考文献：
  名称：

  A Mild and Selective Method for the Catalytic Hydrodeoxygenation of Cyanurate Activated Phenols in Multiphasic Continuous Flow

  摘要：

  sA low-energy, high-selectivity approach to the catalytic hydrodeoxygenation of phenols is reported using batch or continuous flow methods to react 3 equiv of phenol with cyanuric chloride then hydrogenolyzing the triarylcyanurate intermediate to give 3 equiv of deoxo aromatic. The use of cyanuric chloride compares favorably with existing activation methods, showing improved scalability, atom efficiency, and economics. The scope of both the activation and hydrogenolysis stages are explored using lignin-related phenols. Initial development has identified that continuous stir tank reactors (CSTRs) enable a multiphasic process for converting guaiacol to anisole and at steady state overcome the catalyst deactivation issues observed in batch, seemingly caused by the cyanurate byproduct. Green chemistry aspects and the potential for industrial adoption are discussed.

  DOI：

  10.1021/acs.oprd.6b00314

文献信息

• Triazine compounds, polymers comprising triazine structural units, and method
  申请人：General Electric Company

  公开号：US20030078347A1

  公开（公告）日：2003-04-24

  In various embodiments the present invention comprises 2,4,6-trisubstituted-1,3,5-triazine capping agents comprising one, two, or three leaving groups as substituents with any remaining substituents being essentially inert to reaction with a nucleophilic group on a polymer or monomer, or reactive with a nucleophilic group on a polymer or monomer at a slower rate than any leaving group. The invention also comprises polymers or monomers with nucleophilic groups capped with a triazine moiety. Still other embodiments of the invention comprise processes for capping nucleophilic groups in a polymer or monomer which comprises combining and reacting the polymer or monomer with a triazine-comprising capping agent.

  在各种实施例中，本发明包括具有一个、两个或三个离去基团作为取代基的2,4,6-三取代-1,3,5-三嗪封顶剂，其余取代基本质上对与聚合物或单体上的亲核基团反应是惰性的，或者与聚合物或单体上的亲核基团反应的速率比任何离去基团慢。本发明还包括具有三嗪基团封顶的含有亲核基团的聚合物或单体。本发明的其他实施例还包括封顶聚合物或单体中的亲核基团的过程，其中包括将聚合物或单体与含三嗪的封顶剂结合并反应。
• TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD
  申请人：Brown Bruce Sterling

  公开号：US20080097040A1

  公开（公告）日：2008-04-24

  In various embodiments the present invention comprises 2,4,6-trisubstituted-1,3,5-triazine capping agents comprising one, two, or three leaving groups as substituents with any remaining substituents being essentially inert to reaction with a nucleophilic group on a polymer or monomer, or reactive with a nucleophilic group on a polymer or monomer at a slower rate than any leaving group. The invention also comprises polymers or monomers with nucleophilic groups capped with a triazine moiety. Still other embodiments of the invention comprise processes for capping nucleophilic groups in a polymer or monomer which comprises combining and reacting the polymer or monomer with a triazine-comprising capping agent.

  在各种实施方式中，本发明包括2,4,6-三取代-1,3,5-三嗪封端剂，其中包括一个、两个或三个离去基团作为取代基，其余取代基基本上对与聚合物或单体上的亲核基反应无反应性，或者与聚合物或单体上的亲核基反应速率比任何离去基团慢。本发明还包括具有嘧啶基团封端的聚合物或单体。本发明的其他实施方式还包括用嘧啶类封端剂封闭聚合物或单体中的亲核基的过程，其中包括将聚合物或单体与含三嗪的封端剂结合并反应。
• TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP1423372A2

  公开（公告）日：2004-06-02
• US7235611B2
  申请人：——

  公开号：US7235611B2

  公开（公告）日：2007-06-26
• US7547749B2
  申请人：——

  公开号：US7547749B2

  公开（公告）日：2009-06-16