3,15-diphenyl-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,15-diphenyl-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane
• 英文别名: 3,15-diphenyl-7,11,18,21-tetraoxatrispiro[5.2.2.512.29.26]henicosane
• 化学式: C₂₉H₃₆O₄
• 分子量: 448.602
• InChiKey: YWEQKRAKRJARNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  33
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  季戊四醇 、 4-苯基环己酮 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 以75%的产率得到3,15-diphenyl-7,11,18,21-tetraoxatrispiro[5.2.2.5.2.2]henicosane
  参考文献：
  名称：

  Synthesis and Stereochemistry of Some New Trispiro-1,3-dioxaneswith Axial and Helical Chirality

  摘要：

  The stereoisomerism of some trispiro-1,3-dioxanes obtained from substituted cyclohexanones and pentaerithrytol is discussed considering the possible trispiro-6,9-syn-9,12-syn, trispiro-6,9-syn-9,12-anti, and trispiro-6,9-anti-9,12-anti structures of the spiro skeleton and the characteristic axial and helical chirality of spiranes with six-membered rings. The influence of the presence of chiral carbon atoms and of the peculiar conformational behaviour of the molecules on the stereoisomerism of the these compounds is elucidated.

  DOI：

  10.1007/pl00010105

文献信息

• Synthesis and Stereochemistry of Some New Trispiro-1,3-dioxaneswith Axial and Helical Chirality
  作者：Ion Grosu、Sorin Mager、Gerard Plé、Istvan Turos、Eugen Mesaros、Iosefina Schirger

  DOI：10.1007/pl00010105

  日期：1998.1

  The stereoisomerism of some trispiro-1,3-dioxanes obtained from substituted cyclohexanones and pentaerithrytol is discussed considering the possible trispiro-6,9-syn-9,12-syn, trispiro-6,9-syn-9,12-anti, and trispiro-6,9-anti-9,12-anti structures of the spiro skeleton and the characteristic axial and helical chirality of spiranes with six-membered rings. The influence of the presence of chiral carbon atoms and of the peculiar conformational behaviour of the molecules on the stereoisomerism of the these compounds is elucidated.