3-dimethylamino-2-chloro-4,4-ethylenedioxycyclopent-2-en-1-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-dimethylamino-2-chloro-4,4-ethylenedioxycyclopent-2-en-1-one
• 英文别名: 2-chloro-3-dimethylamino-4,4-ethylenedioxy-2-cyclopentenone；2-chloro-3-dimethylamino-4,4-ethylenedioxycyclopent-2-enone；6-dimethylamino-7-chloro-1,4-dioxaspiro[4.4]non-6-en-8-one；8-chloro-9-(dimethylamino)-1,4-dioxaspiro[4.4]non-8-en-7-one
• 化学式: C₉H₁₂ClNO₃
• 分子量: 217.652
• InChiKey: ZYHYICUKTVCATH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,3,5-Trichloro-4,4-ethylenedioxy-2-cyclopenten-1-one 、 三(二甲胺基)膦 以 四氢呋喃 为溶剂， 以80%的产率得到3-dimethylamino-2-chloro-4,4-ethylenedioxycyclopent-2-en-1-one
  参考文献：
  名称：

  Reactions of (Me2N)3P with functionalized di- and trichlorocyclopentenones

  摘要：

  2,3-Dichloro-4,4-ethylenedioxycyclopent-2-enone, its 5-chloroderivative, and 5-allyl-2,3,5-trichloro-4,4-dimethoxycyclopent-2-enone react with (Me2N)(3)P to give the corresponding products of substitution of the NMe2 group for the vinylic Cl atom at C(3).

  DOI：

  10.1007/bf02641560

文献信息

• ——
  作者：R. R. Akhmetvaleev、G. A. Shavaleeva、G. M. Baibulatova、M. S. Miftakhov

  DOI：10.1023/a:1013156326836

  日期：——
• ——
  作者：N. A. Ivanova、A. M. Shainurova、A. A. Khusainova、O. V. Shitikova、R. R. Akhmetvaleev、M. S. Miftakhov

  DOI：10.1023/a:1016534819847

  日期：——

  By reaction of 6,7-dichloro-1,4-dioxaspiro[4.4]non-6-en-8-one with NaI and LiBr in boiling acetylacetone or methyl butyl ketone the corresponding 3-iodo and 3-bromo derivatives of cyclopentenone were prepared.
• Reactions of (Me2N)3P with functionalized di- and trichlorocyclopentenones
  作者：R. R. Akhmetvaleev、T. A. Belogaeva、G. M. Karimova、M. S. Miftakhov

  DOI：10.1007/bf02641560

  日期：1998.12

  2,3-Dichloro-4,4-ethylenedioxycyclopent-2-enone, its 5-chloroderivative, and 5-allyl-2,3,5-trichloro-4,4-dimethoxycyclopent-2-enone react with (Me2N)(3)P to give the corresponding products of substitution of the NMe2 group for the vinylic Cl atom at C(3).