5-methyl-octa-1,3,5-triene

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 5-methyl-octa-1,3,5-triene
• 英文别名: 5-Methyl-octa-1,3,5-trien；4-Methyl-3,5,7-octatriene；5-methylocta-1,3,5-triene
• 化学式: C₉H₁₄
• 分子量: 122.21
• InChiKey: TUIYJCVQHOAQSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-甲基-2-戊烯醛 在 potassium hydrogensulfate 、 乙醚 、 锌 作用下， 生成 5-methyl-octa-1,3,5-triene
  参考文献：
  名称：

  Microbiological survey of dialysate: Vantage of use of sterile bag concentrate

  摘要：

  SummaryHaemodialysed patients are exposed to nearly 400 litres of dialysis water weekly. The bacterial contamination of treated dialysate and water induces acute pyrogenic reactions or chronic damage and cytokine activation.The aim of this study was to value the microbiological parameters of dialysis water and dialysate of our monitors by bacterial culture (measured as colony forming units [CFU]) of water samples at 37 °C after 48 hours, at 22 °C after 72 hours and after seven days, and by measuring endotoxin levels (endotoxin units [EU]).In our centre, there are 16 monitors (6 monitors use sterile dialysate fluid and 10 monitors use non sterile dialysate fluid). The chemicals used for disinfection are chlorine and paracetic acid. Water samples were taken under sterile procedures every three months for a year.No bacteria were found in the samples of water of the dialysis ring; EU were lower than the limit value of 0.25 EU/ml fixed by the European Pharmacopoeia.The concentration of CFU and EU of the dialysate, taken from monitors with a sterile bag, were lower than those of other monitors (p < 0.05 t Student test). However, the levels of CFU/ml and EU/ml of dialysate samples, taken from monitors with a non‐sterile bag, were lower than the guideline value of the European Pharmacopoeia (v.n. CFU < 50 CFU/ml and EU < 0,05 EU/ml).Frequent examination of CFU and EU is essential to reduce the damage caused by the use of contaminated water, therefore the goal of future dialytic techniques will be the use of “sterile dialysate”.

  DOI：

  10.1111/j.1755-6686.2001.tb00160.x

文献信息

• Microbiological survey of dialysate: Vantage of use of sterile bag concentrate
  作者：S. Pansini、R. Degaetano、D. Boccassini、E. Turi

  DOI：10.1111/j.1755-6686.2001.tb00160.x

  日期：2001.7.9

  SummaryHaemodialysed patients are exposed to nearly 400 litres of dialysis water weekly. The bacterial contamination of treated dialysate and water induces acute pyrogenic reactions or chronic damage and cytokine activation.The aim of this study was to value the microbiological parameters of dialysis water and dialysate of our monitors by bacterial culture (measured as colony forming units [CFU]) of water samples at 37 °C after 48 hours, at 22 °C after 72 hours and after seven days, and by measuring endotoxin levels (endotoxin units [EU]).In our centre, there are 16 monitors (6 monitors use sterile dialysate fluid and 10 monitors use non sterile dialysate fluid). The chemicals used for disinfection are chlorine and paracetic acid. Water samples were taken under sterile procedures every three months for a year.No bacteria were found in the samples of water of the dialysis ring; EU were lower than the limit value of 0.25 EU/ml fixed by the European Pharmacopoeia.The concentration of CFU and EU of the dialysate, taken from monitors with a sterile bag, were lower than those of other monitors (p < 0.05 t Student test). However, the levels of CFU/ml and EU/ml of dialysate samples, taken from monitors with a non‐sterile bag, were lower than the guideline value of the European Pharmacopoeia (v.n. CFU < 50 CFU/ml and EU < 0,05 EU/ml).Frequent examination of CFU and EU is essential to reduce the damage caused by the use of contaminated water, therefore the goal of future dialytic techniques will be the use of “sterile dialysate”.