2,2,3,3-tetrachloro-1,4-diphenylbutan-1,4-diol

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: 2,2,3,3-tetrachloro-1,4-diphenylbutan-1,4-diol
• 英文别名: 2,2,3,3-tetrachloro-1,4-diphenylbutane-1,4-diol
• 化学式: C₁₆H₁₄Cl₄O₂
• 分子量: 380.098
• InChiKey: KDTGIYBTGSSRMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  22.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  40.46
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  苯甲醛 、 1,1,2,2-四氯乙烷 在 碘苯 、 tetrabutylammonium tetrafluoroborate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 5.6h， 以31%的产率得到2,2,3,3-tetrachloro-1,4-diphenylbutan-1,4-diol
  参考文献：
  名称：

  Direct electroreduction or use of an electrogenerated base : two ways for the coupling of polyhalogenated compounds with aldehydes or ketones.

  摘要：

  The electrochemical coupling of polyhalogenated compounds with carbonyl compounds is achieved in two ways. A carbanion RX(n)(-) is generated either by the direct electroreduction of RX(n)Cl or by deprotonation of RX(n)H. In this latter case the base Ph(-) is electrogenerated by reduction of iodobenzene. All electrolysis were carried out in an undivided cell fitted with a cadmium-coated cathode and an aluminium or magnesium sacrificial anode. (C) 1997, Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(96)01073-3

文献信息

• Direct electroreduction or use of an electrogenerated base : two ways for the coupling of polyhalogenated compounds with aldehydes or ketones.
  作者：Rachid Barhdadi、Blandine Simsen、Michel Troupel、Jean-Yves Nédélec

  DOI：10.1016/s0040-4020(96)01073-3

  日期：1997.2

  The electrochemical coupling of polyhalogenated compounds with carbonyl compounds is achieved in two ways. A carbanion RX(n)(-) is generated either by the direct electroreduction of RX(n)Cl or by deprotonation of RX(n)H. In this latter case the base Ph(-) is electrogenerated by reduction of iodobenzene. All electrolysis were carried out in an undivided cell fitted with a cadmium-coated cathode and an aluminium or magnesium sacrificial anode. (C) 1997, Elsevier Science Ltd.