isopanepoxydone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: isopanepoxydone
• 英文别名: (1R,5S,6R)-5-hydroxy-4-[(E)-3-hydroxy-3-methylbut-1-enyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: STLLXMKVZSLHGS-ZSRXNTIOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  70.1
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-甲基-3-丁烯-2-醇 在 palladium diacetate 邻苯二甲酸二甲酯 、 四丁基氟化铵 、 氨 、 silver carbonate 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 生成 isopanepoxydone
  参考文献：
  名称：

  Efficient stereoselective syntheses of isopanepoxydone and panepoxydone: a re-assignment of relative configuration

  摘要：

  Recent efforts in our laboratories have resulted in efficient racemic syntheses of isopanepoxydone and panepoxydone, secondary metabolites isolated originally from the basidiomycete Panus conchatus. These synthetic efforts have led us to assign the structure of isopanepoxydone as that of 3 and re-assign the structure of panepoxydone as 2. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01736-6

文献信息

• Efficient stereoselective syntheses of isopanepoxydone and panepoxydone: a re-assignment of relative configuration
  作者：J.Brad Shotwell、Shaojing Hu、Eva Medina、Megumi Abe、Roger Cole、Craig M Crews、John L Wood*

  DOI：10.1016/s0040-4039(00)01736-6

  日期：2000.12

  Recent efforts in our laboratories have resulted in efficient racemic syntheses of isopanepoxydone and panepoxydone, secondary metabolites isolated originally from the basidiomycete Panus conchatus. These synthetic efforts have led us to assign the structure of isopanepoxydone as that of 3 and re-assign the structure of panepoxydone as 2. (C) 2000 Elsevier Science Ltd. All rights reserved.