全氟己基乙基二甲基丁醚 | 210896-25-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 全氟己基乙基二甲基丁醚
• 英文名称: 1H,1H,2H,2H-perfluorooctyl 1,3-dimethylbutyl ether
• 英文别名: 2-(perfluorohexyl)ethyl 1,3-dimethylbutyl ether；F-626；Perfluorohexylethyl dimethylbutyl ether；1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-(4-methylpentan-2-yloxy)octane
• CAS: 210896-25-6
• 化学式: C₁₄H₁₇F₁₃O
• 分子量: 448.268
• InChiKey: REMSMUILZZYKPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  14

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟-1-辛醇	1H,1H,2H,2H-tridecafluoro-n-octanol	647-42-7	C8H5F13O	364.106

反应信息

• 作为产物：
  描述：

  3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟-1-辛醇 、 4-甲基-2-戊酮 在 palladium on activated charcoal 氢气 作用下， 反应 8.0h， 以92%的产率得到全氟己基乙基二甲基丁醚
  参考文献：
  名称：

  一种从醇和羰基化合物合成醚的简便催化方法

  摘要：

  二烷基醚和烷基氟烷基醚是由醇和羰基化合物在Pd/C存在下，在氢气、W...

  DOI：

  10.1246/bcsj.78.456

文献信息

• A new fluorous/organic amphiphilic ether solvent, F-626: execution of fluorous and high temperature classical reactions with convenient biphase workup to separate product from high boiling solvent
  作者：Hiroshi Matsubara、Shinji Yasuda、Hiroyuki Sugiyama、Ilhyong Ryu、Yasuyuki Fujii、Katsumi Kita

  DOI：10.1016/s0040-4020(02)00256-9

  日期：2002.5

  A new fluorous/organic amphiphilic ether solvent, 1H,1H,2H,2H-perfluorooctyl 1,3-dimethylbutyl ether (F-626), is introduced. The basic properties of F-626, especially the partition coefficients with organic solvents/FC-72 (perfluorohexane), were investigated. F-626 was easy to remove by fluorous biphase treatment. Using F-626 as a solvent, LAH reduction, catalytic hydrogenation, and fluorous reductive radical reactions were successful. Classical high temperature reactions up to 200degreesC, such as the Vilsmeier formylation, the Wolff-Kishner reduction, and the Diels-Alder reaction, were also examined in F-626. The yields of the products in F-626 were almost comparable with those conducted in common organic solvents, which prove that F-626 has the potential to be an easily recyclable high boiling solvent. (C) 2002 Elsevier Science Ltd. All rights reserved.
• US6060626A
  申请人：——

  公开号：US6060626A

  公开（公告）日：2000-05-09
• A Convenient Catalytic Method for the Synthesis of Ethers from Alcohols and Carbonyl Compounds
  作者：Yasuyuki Fujii、Hisakazu Furugaki、Eiko Tamura、Shinji Yano、Katsumi Kita

  DOI：10.1246/bcsj.78.456

  日期：2005.3

  Dialkyl ethers and alkyl fluoroalkyl ethers are obtained in excellent yields by the reaction of alcohols and carbonyl compounds in the presence of Pd/C under the atmospheric pressure of hydrogen, w...

  二烷基醚和烷基氟烷基醚是由醇和羰基化合物在Pd/C存在下，在氢气、W...