Magnone A

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 呋喃类木脂素
• 英文名称: Magnone A
• 英文别名: (3,4-dimethoxyphenyl)-[(3R,4R,5S)-5-(3,4-dimethoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methanone
• 化学式: C₂₂H₂₆O₇
• 分子量: 402.4
• InChiKey: PYUASVNLYYZKLA-PONJGIIJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Natural preservatives and antimicrobial agents, including compositions thereof
  申请人：Unigen, Inc.

  公开号：US10780173B2

  公开（公告）日：2020-09-22

  Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.

  本文公开的组合物包括至少一种白花蛇舌草提取物和一种厚朴提取物的混合物。在某些实施方案中，组合物包括至少一种富含一种或多种大环生物碱的白花蛇舌草提取物和至少一种富含一种或多种木脂素的厚朴提取物的混合物。
• Platelet-activated factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents
  申请人：——

  公开号：US20040028756A1

  公开（公告）日：2004-02-12

  Antagonists to platelet-activating factor provide analgesic effects as well as limit the release of inflammatory mediators. Use of these antagonists in the form of pharmaceutical compositions or nutritionals is beneficial (1) in the treatment of acute and/or chronic pain; (2) in the inhibition of inappropriate or excessive contraction of the uterus; (3) in the treatment of septic shock; and (4) in the inhibition of angiogenesis and/or tumor cell proliferation.

  血小板活化因子拮抗剂具有镇痛效果，并能限制炎症介质的释放。以药物组合物或营养品的形式使用这些拮抗剂有利于：(1) 治疗急性和/或慢性疼痛；(2) 抑制子宫不适当或过度收缩；(3) 治疗脓毒性休克；以及 (4) 抑制血管生成和/或肿瘤细胞增殖。
• Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents
  申请人：Wurtman J. Richard

  公开号：US20050032713A1

  公开（公告）日：2005-02-10

  Antagonists to platelet-activating factor provide analgesic effects as well as limit the release of inflammatory mediators. Use of these antagonists in the form of pharmaceutical compositions or nutritionals is beneficial (1) in the treatment of acute and/or chronic pain; (2) in the inhibition of inappropriate or excessive contraction of the uterus; (3) in the treatment of septic shock; and (4) in the inhibition of angiogenesis and/or tumor cell proliferation.

  血小板活化因子拮抗剂具有镇痛效果，并能限制炎症介质的释放。以药物组合物或营养品的形式使用这些拮抗剂有利于：(1) 治疗急性和/或慢性疼痛；(2) 抑制子宫不适当或过度收缩；(3) 治疗脓毒性休克；以及 (4) 抑制血管生成和/或肿瘤细胞增殖。
• NATURAL PRESERVATIVES AND ANTIMICROBIAL AGENTS, INCLUDING COMPOSITIONS THEREOF
  申请人：Unigen, Inc.

  公开号：EP3373946A1

  公开（公告）日：2018-09-19
• Natural Preservatives and Antimicrobial Agents, Including Compositions Thereof
  申请人：Unigen, Inc.

  公开号：US20170173162A1

  公开（公告）日：2017-06-22

  Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.