1-cyclopropyl-8-methoxy-4-oxo-7-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-1,4-dihydro-3-quinolinecarboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-cyclopropyl-8-methoxy-4-oxo-7-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-1,4-dihydro-3-quinolinecarboxylic acid
• 英文别名: 1-Cyclopropyl-8-methoxy-4-oxo-7-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)quinoline-3-carboxylic acid
• 化学式: C₂₁H₂₀N₂O₄S
• 分子量: 396.467
• InChiKey: ZCOGPDQBDZUNRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  107
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Quinoline derivatives
  申请人：CADILA HEALTHCARE LIMITED

  公开号：EP1927589A1

  公开（公告）日：2008-06-04

  The present invention relates to novel compounds of general formula (I), their tautomeric forms, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process for preparing compounds of general formula (I), their tautomeric forms, their pharmaceutically acceptable salts and pharmaceutical compositions containing them.

  本发明涉及一般式(I)的新化合物，它们的互变异构形式，它们的药学上可接受的盐以及含有它们的药物组合物。本发明还涉及一种制备一般式(I)化合物、它们的互变异构形式、药学上可接受的盐以及含有它们的药物组合物的方法。
• Novel quinoline derivatives
  申请人：Srivastava Brijesh Kumar

  公开号：US20080139574A1

  公开（公告）日：2008-06-12

  The present invention relates to novel compounds of general formula (I), their tautomeric forms, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process for preparing compounds of general formula (I), their tautomeric forms, their pharmaceutically acceptable salts and pharmaceutical compositions containing them.

  本发明涉及一般式(I)的新化合物，它们的互变异构形式，它们的药用盐及含有它们的药物组合物。本发明还涉及一种用于制备一般式(I)化合物、它们的互变异构形式、药用盐及含有它们的药物组合物的方法。
• Quinoline and naphthyridine carboxylic acid antibacterials
  申请人：——

  公开号：US20020049223A1

  公开（公告）日：2002-04-25

  Compounds having formula (I) 1 or pharmaceutically acceptable salts or prodrugs thereof, are useful as antibacterial agents.

  具有化学式(I)1的化合物或其药用可接受的盐或前药，可用作抗菌剂。