双环[2.2.1]庚-1-基乙酸酯 | 93980-80-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 双环[2.2.1]庚-1-基乙酸酯
• 英文名称: 1-norbornyl acetate
• 英文别名: Norbornyl-acetat；Norbornyl-(1)-acetat；bicyclo[2.2.1]hept-1-yl acetate；norbornyl acetate；Bicyclo(2.2.1)hept-1-yl acetate；1-bicyclo[2.2.1]heptanyl acetate
• CAS: 93980-80-4
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: RVIORAABVUOPRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915390090

反应信息

• 作为产物：
  描述：

  N-(1-norbornyl)-N',N'-dimethyl-N-nitrosourea 以14%的产率得到
  参考文献：
  名称：

  WHITE, E. H.;RYAN, T. J.;HAHN, BO, SUP;ERICKSON, R. H., J. ORG. CHEM., 1984, 49, N 25, 4860-4866

  摘要：

  DOI：

文献信息

• DERMATOLOGICAL COMPOSITIONS AND METHODS
  申请人：——

  公开号：US20020141952A1

  公开（公告）日：2002-10-03

  Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

  公开了用于调节哺乳动物黑素细胞的黑色素含量的方法及组合物；通过施用包括醇、二醇和/或三醇及其类似物在内的各种化合物，来调节哺乳动物皮肤、毛发、羊毛或毛皮的色素沉着；以及治疗或预防各种皮肤和增殖性障碍。
• Preparation of alkyl carboxylates
  申请人：Mobil Oil Corporation

  公开号：US04448983A1

  公开（公告）日：1984-05-15

  A process for preparation of alkyl carboxylate mixtures enriched in alpha-methylalkyl carboxylate compounds, by reaction of an olefin and a carboxylic acid compound in the presence of a particular type of zeolite catalyst. The zeolites are characterized by a silica to alumina mole ratio of at least 12 and a constraint index of 1 to 12. Zeolites ZSM-5 and ZSM-12 are particularly preferred.

  一种制备富含α-甲基烷基羧酸酯化合物的烷基羧酸酯混合物的方法，通过在特定类型的沸石催化剂存在下，将烯烃和羧酸化合物反应。该沸石的硅铝比至少为12，限制指数为1至12。特别优选ZSM-5和ZSM-12沸石。
• Method for the selective preparation of secondary alcohols and
  申请人：Mobil Oil Corporation

  公开号：US04461729A1

  公开（公告）日：1984-07-24

  A method for preparation of secondary alcohol mixtures by selective reaction of an olefin or olefin mixture and a carboxylic acid compound in the presence of a particular type of shape selective zeolite catalyst. The reaction selectively produces .alpha.-methylalkyl carboxylate enriched ester product which, upon subsequent hydrolysis, yields the desired 2-alcohol enriched secondary alcohol product.

  本发明提供了一种制备次级醇混合物的方法，该方法通过在特定类型的形状选择性沸石催化剂存在下，选择性地反应烯烃或烯烃混合物和羧酸化合物，从而选择性地产生α-甲基烷基羧酸酯富集的酯类产物，随后通过水解产生所需的2-醇富集的次级醇产品。
• PROCESS FOR PRODUCING OPTICALLY ACTIVE NORBORNEOL
  申请人：SHIONOGI SEIYAKU KABUSHIKI KAISHA

  公开号：EP0570593A1

  公开（公告）日：1993-11-24

  A process for producing optically active norborneol comprising the step of bringing a (±)-exo-norbornane type ester represented by formula (I) into contact with a microorganism, which may be optionally treated, selected from among those belonging to the genera Pseudomonas, Acetobacter, Arthrobacter, Rhodotorula and Saccharomyces. A simple post-treatment of the product gives rise to highly pure (+)- and/or (-)-exo-norbornane type alcohol in high yields.

  一种生产光学活性降冰片醇的工艺，包括将式（I）所代表的(±)-外-降冰片烷型酯与微生物接触的步骤，该微生物可从假单胞菌属、醋酸菌属、节杆菌属、罗氏菌属和酵母菌属中任选一种进行处理。只需对产品进行简单的后处理，就能得到高纯度的(+)-和/或(-)-外降冰片烷型醇，产量高。
• Norbornane type ester hydrolase
  申请人：SHIONOGI & CO., LTD.

  公开号：EP0623678A2

  公开（公告）日：1994-11-09

  A norbornane type ester hydrolase that enantio-selectively hydrolyzes a (±)-exo-norbornane type ester represented by Formula I is provided : wherein R is acyl, and A and B are hydrogens, respectively, or where A and B are absent, resulting in a carbon-carbon double bond between the carbons to which A and B are attached in Formula I. The norbornane type ester hydrolase has an optimal pH of approximately 8 and a stable pH range of approximately 6 to 8.

  提供了一种降冰片烷型酯水解酶，它能对映选择性地水解式 I 所代表的 (±)- 外-降冰片烷型酯： 其中 R 是酰基，A 和 B 分别是氢，或者 A 和 B 不存在，从而在式 I 中 A 和 B 所连接的碳之间形成碳碳双键。降冰片烷型酯水解酶的最佳 pH 值约为 8，稳定 pH 值范围约为 6 至 8。