2-oxopropyl (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-oxopropyl (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate
• 化学式: C₂₃H₃₂O₃
• 分子量: 356.5
• InChiKey: WYLFKKHGPWTZRY-XNJDZTGNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Use of 13-transretinoic acid esters for the treatment of skin cancer and photoaging
  申请人：Molecular Design International, Inc.

  公开号：EP0643959A1

  公开（公告）日：1995-03-22

  The present invention provides the use of amides and esters of 13-trans-retinoic acid in the manufacture of medicaments for the treatment of skin cancer or photoaging of skin.

  本发明提供了 13-反式维甲酸酰胺和酯在制造治疗皮肤癌或皮肤光老化药物中的用途。
• ESTERS OF 13-TRANS-RETINOIC ACID
  申请人：MOLECULAR DESIGN INTERNATIONAL, INC.

  公开号：EP0366713B1

  公开（公告）日：1994-06-08
• Topical compositions for treatment of skin conditions
  申请人：Purcell William Paul

  公开号：US20080139518A1

  公开（公告）日：2008-06-12

  The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit.
• TOPICAL COMPOSITIONS FOR TREATMENT OF SKIN CONDITIONS
  申请人：CONCERT, LLC

  公开号：US20130237505A1

  公开（公告）日：2013-09-12

  The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit.
• US4885311A
  申请人：——

  公开号：US4885311A

  公开（公告）日：1989-12-05