(1SR)-1-((3RS)-4-methyl-1-penten-3-yl)-2-(1-methylethylidene)cyclohexanol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1SR)-1-((3RS)-4-methyl-1-penten-3-yl)-2-(1-methylethylidene)cyclohexanol
• 英文别名: (1S)-1-[(3R)-4-methylpent-1-en-3-yl]-2-propan-2-ylidenecyclohexan-1-ol
• 化学式: C₁₅H₂₆O
• 分子量: 222.371
• InChiKey: GPVCQOCPMHNSEC-ZFWWWQNUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-(丙烷-2-基)环己酮 、 4-methyl-2-pentenylmagnesium chloride 以75%的产率得到(1SR)-1-((3RS)-4-methyl-1-penten-3-yl)-2-(1-methylethylidene)cyclohexanol
  参考文献：
  名称：

  Stereochemistry of addition of allylic Grignard reagents to .alpha.,.beta.-ethylenic ketones

  摘要：

  The stereochemistry of the addition of allylic Grignard reagents, (mainly crotylmagnesium chloride) to various conjugated enones has been investigated and a compact transition state is postulated. For s-cis-enones bearing no bulky substituents, a boat transition state, involving a trans-crotylmagnesium chloride, occurs leading to erythro-1,5-hexadien-3-ols as the major or only product.

  DOI：

  10.1021/jo00062a009

文献信息

• Zair Touriya, Santelli-Rouvier Christiane, Santelli Maurice, J. Org. Chem, 58 (1993) N 10, S 2686-2693
  作者：Zair Touriya, Santelli-Rouvier Christiane, Santelli Maurice

  DOI：——

  日期：——
• Stereochemistry of addition of allylic Grignard reagents to .alpha.,.beta.-ethylenic ketones
  作者：Touriya Zair、Christiane Santelli-Rouvier、Maurice Santelli

  DOI：10.1021/jo00062a009

  日期：1993.5

  The stereochemistry of the addition of allylic Grignard reagents, (mainly crotylmagnesium chloride) to various conjugated enones has been investigated and a compact transition state is postulated. For s-cis-enones bearing no bulky substituents, a boat transition state, involving a trans-crotylmagnesium chloride, occurs leading to erythro-1,5-hexadien-3-ols as the major or only product.