[(2S,3S,4R,6R)-6-[[(5S,6R,7E,9S,11Z,13S,16S,17S,18S,20S,21R,22S)-3-formyl-5,25-dihydroxy-9-[(2R,4S,5R,6R)-5-(methoxycarbonylamino)-4,6-dimethyl-4-nitrooxan-2-yl]oxy-8,12,18,20,22-pentamethyl-23,27-dioxo-26-oxapentacyclo[22.2.1.01,6.013,22.016,21]heptacosa-2,7,11,14,24-pentaen-17-yl]oxy]-4-[(2S,5R,6S)-5-[(2S,4R,5R,6S)-4-hydroxy-5-[(2S,5R,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-methyloxan-3-yl] acetate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: [(2S,3S,4R,6R)-6-[[(5S,6R,7E,9S,11Z,13S,16S,17S,18S,20S,21R,22S)-3-formyl-5,25-dihydroxy-9-[(2R,4S,5R,6R)-5-(methoxycarbonylamino)-4,6-dimethyl-4-nitrooxan-2-yl]oxy-8,12,18,20,22-pentamethyl-23,27-dioxo-26-oxapentacyclo[22.2.1.01,6.013,22.016,21]heptacosa-2,7,11,14,24-pentaen-17-yl]oxy]-4-[(2S,5R,6S)-5-[(2S,4R,5R,6S)-4-hydroxy-5-[(2S,5R,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-methyloxan-3-yl] acetate
• 化学式: C67H96N2O24
• 分子量: 1313.5
• InChiKey: KAJYHKRSEVHEGX-HCQSHQBASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  93
• 可旋转键数：
  15
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  344
• 氢给体数：
  5
• 氢受体数：
  24

文献信息

• ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN
  申请人：DeFrees Shawn

  公开号：US20070042458A1

  公开（公告）日：2007-02-22

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.