N-geranyl-N'-allyl-N'-(cyclopentyl)ethane-1,2-diamine | 502487-69-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: N-geranyl-N'-allyl-N'-(cyclopentyl)ethane-1,2-diamine
• 英文别名: N'-allyl-N'-cyclopentyl-N-[(2E)-3,7-dimethylocta-2,6-dienyl]ethane-1,2-diamine；N'-cyclopentyl-N-[(2E)-3,7-dimethylocta-2,6-dienyl]-N'-prop-2-enylethane-1,2-diamine
• CAS: 502487-69-6
• 化学式: C₂₀H₃₆N₂
• 分子量: 304.519
• InChiKey: PVPUCBTYLHHNMK-CPNJWEJPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Methods of use and compositions for the diagnosis and treatment of infectious disease
  申请人：——

  公开号：US20030236225A1

  公开（公告）日：2003-12-25

  Methods and compositions for treating disease caused by microorganisms, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.

  方法和组合物用于治疗由微生物引起的疾病，特别是结核病。具体而言，提供了用于治疗传染病的取代乙烯二胺的方法和组合物。在一种实施方式中，这些方法和组合物用于治疗分枝杆菌感染，包括但不限于结核病。
• ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS
  申请人：PROTOPOPOVA Marina Nikolaevna

  公开号：US20090192173A1

  公开（公告）日：2009-07-30

  Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis. In certain embodiments, the present invention comprises compositions comprising novel substituted ethylene diamine compounds further comprising antitubercular agents such as rifampicin, isoniazid, pyrazinamide and ethambutol.

  本发明提供了用于治疗由传染性病原体引起的疾病，特别是结核病的方法和组合物。具体而言，提供了用于治疗传染病的取代乙二胺的方法和组合物。在一个实施例中，这些方法和组合物用于治疗分枝杆菌感染，包括但不限于结核病。在某些实施例中，本发明包括包含新型取代乙二胺化合物的组合物，进一步包括抗结核药物如利福平、异烟肼、吡嗪酰胺和乙胺丁醇。
• Anti tubercular drug: compositions and methods
  申请人：——

  公开号：US20040033986A1

  公开（公告）日：2004-02-19

  Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.

  治疗由传染性病原体，特别是结核病引起的疾病的方法和组合物。特别是提供了包含取代乙二胺的治疗传染性疾病的方法和组合物。在一个实施方案中，这些方法和组合物用于治疗分枝杆菌感染，包括但不限于结核病。
• ANTI TUBERCULAR DRUG: COMPOSITIONS AND METHODS
  申请人：Department of Health and Human Services

  公开号：EP1513825A2

  公开（公告）日：2005-03-16
• Anti tubercular drug: compostions and methods
  申请人：——

  公开号：US20040019117A1

  公开（公告）日：2004-01-29

  Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.