1,4-β-cellohexaose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-β-cellohexaose
• 英文别名: laminarin hexaose；cellohexaaose；cellohexaose；beta-D-cellohexaose；(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-[(2R,3S,4R,5R,6S)-6-[(2R,3S,4R,5R,6S)-6-[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₃₆H₆₂O₃₁
• 分子量: 990.87
• InChiKey: OCIBBXPLUVYKCH-FYTDUCIRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -13.3
• 重原子数：
  67
• 可旋转键数：
  16
• 环数：
  6.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  506
• 氢给体数：
  20
• 氢受体数：
  31

反应信息

• 作为反应物：
  描述：

  1,4-β-cellohexaose 生成 1,6-脱水-B-D-纤维二糖
  参考文献：
  名称：

  纤维素快速热解的质谱研究

  摘要：

  使用快速热解探针/线性四极杆离子阱质谱仪组合来研究纤维素、纤维二糖、纤维三糖、纤维四糖、纤维五糖和纤维六糖以及纤维二糖的主要快速热解产物（那些首先离开热解表面的产物） 、纤维三聚糖和纤维戊聚糖，在 600°C。如前所述，在低聚糖和纤维素中发现了具有不同支化率的类似产品。然而，对于纤维三聚糖（和纤维戊聚糖）和纤维素，测量了具有相似支化率的相同产品（除了两个）。该结果表明，纤维三聚糖是研究纤维素快速热解的极好小分子替代物，并且纤维素的大多数快速热解产物并非来自还原端。

  DOI：

  10.1255/ejms.1335

文献信息

• Direct synthesis of 1,6-anhydro sugars from unprotected glycopyranoses by using 2-chloro-1,3-dimethylimidazolinium chloride
  作者：Tomonari Tanaka、Wei Chun Huang、Masato Noguchi、Atsushi Kobayashi、Shin-ichiro Shoda

  DOI：10.1016/j.tetlet.2009.02.171

  日期：2009.5

  Various 1,6-anhydro sugars have been synthesized directly from the corresponding unprotected glycopyranoses in excellent yields by using 2-chloro-1,3-dimethylimidazolinium chloride (DMC) as a dehydrative condensing agent. The reactions took place smoothly under mild reaction conditions in aqueous media. The present method would be a practical tool for synthesis of 1,6-anhydro derivatives of mono-saccharides, linear-oligosaccharides, and branched-oligosaccharides. (C) 2009 Elsevier Ltd. All rights reserved.
• Purification and characterization of a novel GH1 beta-glucosidase from Jeotgalibacillus malaysiensis
  作者：Kok Jun Liew、Lily Lim、Hui Ying Woo、Kok-Gan Chan、Mohd Shahir Shamsir、Kian Mau Goh

  DOI：10.1016/j.ijbiomac.2018.04.156

  日期：2018.8

  Beta-glucosidase (BGL) is an important industrial enzyme for food, waste and biofuel processing.Jeotgalibacillus is an understudied halophilic genus, and no beta-glucosidase from this genus has been reported. A novel beta-glucosidase gene (1344 bp) from J. malaysiensis DSM 28777(T) was cloned and expressed in E. coli. The recombinant protein, referred to as BgID5, consists of a total 447 amino acids. BgID5 purified using a Ni-NTA column has an apparent molecular mass of 52 kDa It achieved the highest activity at pH 7 and 65 degrees C. The activity and stability were increased when CaCl2 was supplemented to the enzyme. The enzyme efficiently hydrolyzed salicin and (1 -> 4)-beta-glycosidic linkages such as in cellobiose, cellotriose, cellotetraose, cellopentose, and cellohexanose. Similar to many BGLs, BgID5 was not active towards polysaccharides such as Avicel, carboxymethyl cellulose, Sigmacell cellulose 101, alpha-cellulose and xylan. When BgID5 blended with Cellic (R) Ctec2, the total sugars saccharified from oil palm empty fruit bunches (OPEFB) was enhanced by 4.5%. Based on sequence signatures and tree analyses, BgID5 belongs to the Glycoside Hydrolase family 1. This enzyme is a novel beta-glucosidase attributable to its relatively low sequence similarity with currently known beta-glucosidases, where the closest characterized enzyme is the DT-Bgl from Anoxybacillus sp. DT3-1. (C) 2018 Elsevier B.V. All rights reserved.