喹啉-6-磺酸 | 65433-95-6

• 物质功能分类: 化学试剂 - 有机试剂
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 喹啉-6-磺酸
• 中文别名: 6-喹啉磺酸
• 英文名称: 6-quinolinesulfonic acid
• 英文别名: Chinolin-6-sulfonsaeure；quinoline-6-sulfonic acid；Quinolin-1-ium-6-sulfonate
• CAS: 65433-95-6
• 化学式: C₉H₇NO₃S
• 分子量: 209.225
• InChiKey: PLUQFBYKHVFHMZ-UHFFFAOYSA-N

物化性质

• 熔点：
  258 °C (decomp)
• 密度：
  1.499±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2933499090

反应信息

• 作为反应物：
  描述：

  喹啉-6-磺酸 在 selenium 硫酸 作用下， 反应 2.0h， 以50%的产率得到烟酸
  参考文献：
  名称：

  Sidorov, O. F.; Kosareva, M. A., Journal of applied chemistry of the USSR, 1983, vol. 56, # 1, p. 219 - 220

  摘要：

  DOI：
• 作为产物：
  描述：

  喹啉-8-磺酸 在 硫酸 作用下， 生成 喹啉-6-磺酸
  参考文献：
  名称：

  v. Georgievics, Monatshefte fur Chemie, 1887, vol. 8, p. 644

  摘要：

  DOI：

文献信息

• [EN] 6-SULFONAMIDE QUINOLINE AND CHROMENE DERIVATIVE AS ANDROGEN RECEPTOR ANTAGONISTS<br/>[FR] DERIVES 6-SULFONAMIDE QUINOLEINIQUES ET CHROMENIQUES A TITRE D'ANTAGONISTES DES RECEPTEURS D'ANDROGENE
  申请人：WARNER LAMBERT CO

  公开号：WO2004083204A1

  公开（公告）日：2004-09-30

  The present invention is directed to 6-sulfonamide quinoline and chromene derivatives of the formula (I) with the definitions of M, R1, R2, A and B according to claim 1 and to their use as androgen antagonists.

  本发明涉及公式(I)的6-磺酰胺喹啉和色烯衍生物，其中M、R1、R2、A和B的定义如权利要求1所述，并将其用作雄激素拮抗剂。
• METHOD FOR PRODUCING ALPHA-ALLYLATED CYCLOALKANONE
  申请人：Kao Corporation

  公开号：US20220153671A1

  公开（公告）日：2022-05-19

  Provided is a method with which an α-allylated cycloalkanone is obtained from a cyclic compound cycloalkanone used as a starting material. The method is a method for producing an α-allylated cycloalkanone represented by General Formula (III), and the method includes: a step 1: reacting a compound represented by General Formula (I) and alcohol having 1 or more and 4 or less of carbon atoms in the presence of a first acid catalyst and optionally a dehydrating agent; and a step 2: reacting a crude product obtained in the step 1 and a compound represented by General Formula (II) in the presence of a second acid catalyst to produce an α-allylated cycloalkanone represented by General Formula (III). The step 1 and the step 2 are consecutively performed. In the formulae above, the group -A 1 - (it should be noted that the front bond refers to a bond that binds to the carbon atom C 1 and the back bond refers to a bond that binds to the carbon atom C 2 ) is an alkylene group having 4 or more and 20 or less of carbon atoms that optionally contains a hetero atom and optionally has a substituent, and R 4 is a hydrogen atom or an alkyl group having 1 or more and 4 or less of carbon atoms.

  提供的是一种方法，通过将环状化合物环状酮用作起始材料，得到α-烯丙基化环状酮。该方法是生产由通式（III）表示的α-烯丙基化环状酮的方法，该方法包括：步骤1：在第一酸性催化剂和可选的脱水剂的存在下，使通式（I）表示的化合物和具有1个或多个碳原子和4个或更少碳原子的醇反应; 步骤2：在第二酸性催化剂的存在下，使步骤1得到的粗产品和通式（II）表示的化合物反应，以生产由通式（III）表示的α-烯丙基化环状酮。步骤1和步骤2是连续执行的。在上述公式中，-A1-基团（应注意前面的键指绑定到碳原子C1的键，后面的键指绑定到碳原子C2的键）是具有4个或多个碳原子和20个或少的碳原子的烷基基团，可选地含有杂原子和可选地具有取代基，而R4是氢原子或具有1个或多个碳原子和4个或更少碳原子的烷基基团。
• Ink composition, inkjet recording method, printed material, production method of a planographic printing plate and planographic printing plate
  申请人：Fujifilm Corporation

  公开号：EP1787809A1

  公开（公告）日：2007-05-23

  The present invention provides an ink composition, and inkjet recording method, a printed material, a production method of a planographic printing plate, and a planographic printing plate. The ink composition of the present invention contains a cationically polymerizable compound, a compound that generates an acid when irradiated with a radiation ray, and an onium salt compound that generates an organic acid compound having a basic nitrogen atom when irradiated with a radiation ray.

  本发明提供了一种油墨组合物、喷墨记录方法、印刷材料、平版印刷板的生产方法以及平版印刷板。本发明的油墨组合物包含一种阳离子可聚合化合物、一种在辐射线照射下生成酸的化合物，以及一种在辐射线照射下生成具有碱性氮原子的有机酸化合物的鎓盐化合物。
• METHOD FOR PRODUCING ALPHA-ALLYLATION CYCLOALKANONE
  申请人：Kao Corporation

  公开号：EP3943477A1

  公开（公告）日：2022-01-26

  Provided is a method with which an α-allylated cycloalkanone is obtained from a cyclic compound cycloalkanone used as a starting material. The method is a method for producing an α-allylated cycloalkanone represented by General Formula (III), and the method includes: a step 1: reacting a compound represented by General Formula (I) and alcohol having 1 or more and 4 or less of carbon atoms in the presence of a first acid catalyst and optionally a dehydrating agent; and a step 2: reacting a crude product obtained in the step 1 and a compound represented by General Formula (II) in the presence of a second acid catalyst to produce an α-allylated cycloalkanone represented by General Formula (III). The step 1 and the step 2 are consecutively performed. In the formulae above, the group -A1- (it should be noted that the front bond refers to a bond that binds to the carbon atom C1 and the back bond refers to a bond that binds to the carbon atom C2) is an alkylene group having 4 or more and 20 or less of carbon atoms that optionally contains a hetero atom and optionally has a substituent, and R4 is a hydrogen atom or an alkyl group having 1 or more and 4 or less of carbon atoms.

  本发明提供了一种从用作起始原料的环状化合物环烷酮中获得α-烯丙基环烷酮的方法。该方法是一种生产通式（III）代表的 α-烯丙基环烷酮的方法，该方法包括： 步骤 1：在第一酸催化剂和可选的脱水剂存在下，使通式（I）代表的化合物和具有 1 个或 1 个以上和 4 个或 4 个以下碳原子的醇反应；以及 步骤 2：在第二酸催化剂存在下，使步骤 1 中得到的粗产物和通式（II）代表的化合物反应，生成通式（III）代表的 α-烯丙基环烷酮。步骤 1 和步骤 2 连续进行。在上式中，基团-A1-（应注意，前键是指与碳原子 C1 结合的键，后键是指与碳原子 C2 结合的键）是具有 4 个或 4 个以上、20 个或 20 个以下碳原子的亚烷基，该亚烷基可选择含有一个杂原子，并可选择具有一个取代基，R4 是氢原子或具有 1 个或 1 个以上、4 个或 4 个以下碳原子的烷基。
• Method for producing alpha-allylated cycloalkanone
  申请人：Kao Corporation

  公开号：US11524929B2

  公开（公告）日：2022-12-13

  Provided is a method with which an α-allylated cycloalkanone is obtained from a cyclic compound cycloalkanone used as a starting material. The method is a method for producing an α-allylated cycloalkanone represented by General Formula (III), and the method includes: a step 1: reacting a compound represented by General Formula (I) and alcohol having 1 or more and 4 or less of carbon atoms in the presence of a first acid catalyst and optionally a dehydrating agent; and a step 2: reacting a crude product obtained in the step 1 and a compound represented by General Formula (II) in the presence of a second acid catalyst to produce an α-allylated cycloalkanone represented by General Formula (III). The step 1 and the step 2 are consecutively performed. In the formulae above, the group -A 1 - (it should be noted that the front bond refers to a bond that binds to the carbon atom C 1 and the back bond refers to a bond that binds to the carbon atom C 2 ) is an alkylene group having 4 or more and 20 or less of carbon atoms that optionally contains a hetero atom and optionally has a substituent, and R 4 is a hydrogen atom or an alkyl group having 1 or more and 4 or less of carbon atoms.

  本发明提供了一种从用作起始原料的环状化合物环烷酮中获得α-烯丙基环烷酮的方法。该方法是一种生产通式（III）代表的 α-烯丙基环烷酮的方法，该方法包括： 步骤 1：在第一酸催化剂和可选的脱水剂存在下，使通式（I）代表的化合物和具有 1 个或 1 个以上和 4 个或 4 个以下碳原子的醇反应；以及 步骤 2：在第二酸催化剂存在下，使步骤 1 中得到的粗产物和通式（II）代表的化合物反应，生成通式（III）代表的 α-烯丙基环烷酮。步骤 1 和步骤 2 连续进行。在上式中，基团 -A 1 - 应注意，前键是指与碳原子 C 1 的键，后键指与碳原子 C 2 ）是一个碳原子数为 4 个或 4 个以上、20 个或 20 个以下的亚烷基，该亚烷基可选择含有一个杂原子，并可选择具有一个取代基，且 R 4 是氢原子或具有 1 个或 1 个以上、4 个或 4 个以下碳原子的烷基。

表征谱图