loganin aglycon

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: loganin aglycon
• 英文别名: methyl (1S,4aS,6S,7R,7aS)-1,6-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
• 化学式: C₁₁H₁₆O₅
• 分子量: 228.245
• InChiKey: XWOHZIIPBYAMJX-VXTVJQJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  马钱子苷 在 citrate buffer 、 β-glucosidase 作用下， 以 水 为溶剂， 反应 24.0h， 生成 马钱苷元 、 loganin aglycon
  参考文献：
  名称：

  Modified iridoid glycosides as anti-implantation agents

  摘要：

  Structural modifications in iridoid glycosides and evaluation of their efficacy on adhering capability (in vitro) of immature hamster uterine epithelial cells to the substratum have been studied. Out of 31, eight compounds in vitro, five compounds in utero and two in vivo showed adhesion/implantation preventing activity, respectively. The results provide an indication for further exploration in the line of development of anti-adhesive agents. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0968-0896(01)00105-5

文献信息

• Modified iridoid glycosides as anti-implantation agents
  作者：Anju P Misra、Vijayavitthal T Mathad、Kanwal Raj、Amiya P Bhaduri、Rashmi Tiwari、Anuradha Srivastava、P.K Mehrotra

  DOI：10.1016/s0968-0896(01)00105-5

  日期：2001.11

  Structural modifications in iridoid glycosides and evaluation of their efficacy on adhering capability (in vitro) of immature hamster uterine epithelial cells to the substratum have been studied. Out of 31, eight compounds in vitro, five compounds in utero and two in vivo showed adhesion/implantation preventing activity, respectively. The results provide an indication for further exploration in the line of development of anti-adhesive agents. (C) 2001 Published by Elsevier Science Ltd.