(3R,4R)-4-氨基-5-亚甲基庚烷-1,3,7-三醇 | 1053612-38-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (3R,4R)-4-氨基-5-亚甲基庚烷-1,3,7-三醇
• 英文名称: (3R,4R)-4-amino-5-methylideneheptane-1,3,7-triol
• CAS: 1053612-38-6
• 化学式: C₈H₁₇NO₃
• 分子量: 175.228
• InChiKey: NWWSPUWSBOULKY-HTQZYQBOSA-N

物化性质

• 沸点：
  387.9±42.0 °C(Predicted)
• 密度：
  1.149±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  86.7
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (3R,4R)-4-氨基-5-亚甲基庚烷-1,3,7-三醇 在 盐酸 、 四氯化碳 、 硼烷四氢呋喃络合物 、 双氧水 、 三乙胺 、 三苯基膦 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 (1R,7S,8R)-7-(羟基甲基)-2,3,5,6,7,8-六氢-1H-吡咯里嗪-1-醇
  参考文献：
  名称：

  对映体控制的吡咯烷核苷，（-）-乙炔嘧啶和（-）-己丁胺的合成

  摘要：

  三取代的烯丙醇13和14已通过相应的三氯乙酰亚胺的分子内碘代酰胺化反应转变为单一的异构反式-恶唑啉16，它们已通过共同的中间体被精制为（-）-铂炔1和（-）-hadinecine 2吡咯嗪3。

  DOI：

  10.1016/s0040-4039(96)02371-4
• 作为产物：
  描述：

  [(E,5R)-3-(acetyloxymethyl)-7-[tert-butyl(dimethyl)silyl]oxy-5-hydroxyhept-3-enyl] acetate 在 盐酸 、 碘 、 potassium carbonate 、 氯化铵 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 锌 作用下， 以 甲醇 、 水 、 乙腈 、 叔丁醇 为溶剂， 生成 (3R,4R)-4-氨基-5-亚甲基庚烷-1,3,7-三醇
  参考文献：
  名称：

  对映体控制的吡咯烷核苷，（-）-乙炔嘧啶和（-）-己丁胺的合成

  摘要：

  三取代的烯丙醇13和14已通过相应的三氯乙酰亚胺的分子内碘代酰胺化反应转变为单一的异构反式-恶唑啉16，它们已通过共同的中间体被精制为（-）-铂炔1和（-）-hadinecine 2吡咯嗪3。

  DOI：

  10.1016/s0040-4039(96)02371-4

文献信息

• Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix
  申请人：UT-Battelle, LLC

  公开号：US10240011B2

  公开（公告）日：2019-03-26

  A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said cros slinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.

  一种功能化碳纤维，其表面共价结合了一种含有环氧基团的上浆剂，其中至少有一部分与交联分子以共价键结合，其中每个交联分子都具有至少两个环氧反应基团和至少一个与碳纤维所结合的聚合物基体的官能团反应的自由官能团、其中，至少有一部分所述交联分子通过至少两个环氧反应基团参与上浆剂的至少两个环氧基团之间的交联键。此外，还介绍了由嵌入聚合物基体中的这些功能化碳纤维组成的复合材料。此外，还介绍了生产功能化碳纤维及其复合材料的方法。
• MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN A POLYMERIC MATRIX
  申请人：UT-BATTELLE, LLC

  公开号：US20160102180A1

  公开（公告）日：2016-04-14

  A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said crosslinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.
• MULTIFUNCTIONAL CURING AGENTS AND THEIR USE IN IMPROVING STRENGTH OF COMPOSITES CONTAINING CARBON FIBERS EMBEDDED IN POLYMERIC MATRIX
  申请人：UT-Battelle, LLC

  公开号：US20170166712A1

  公开（公告）日：2017-06-15

  A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said cros slinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.
• US9617398B2
  申请人：——

  公开号：US9617398B2

  公开（公告）日：2017-04-11
• An enantiocontrolled synthesis of pyrrolizidines, (−)-platynecine and (−)-hadinecine
  作者：Sung Ho Kang、Geun Tae Kim、Yong Sang Yoo

  DOI：10.1016/s0040-4039(96)02371-4

  日期：1997.1

  alcohols 13 and 14 have been converted into a single isomeric trans-oxazoline 16via an intramolecular iodoamidation of the corresponding trichloro-acetimidates, which have been elaborated into (−)-platynecine 1 and (−)-hadinecine 2via a common intermediate pyrrolizidine 3.

  三取代的烯丙醇13和14已通过相应的三氯乙酰亚胺的分子内碘代酰胺化反应转变为单一的异构反式-恶唑啉16，它们已通过共同的中间体被精制为（-）-铂炔1和（-）-hadinecine 2吡咯嗪3。