(3alpha,22S,24E)-3,22-二乙酰氧基羊毛甾-7,9(11),24-三烯-26-酸 | 103963-39-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: (3alpha,22S,24E)-3,22-二乙酰氧基羊毛甾-7,9(11),24-三烯-26-酸
• 英文名称: Ganoderic acid R
• 英文别名: (E,5S,6S)-5-acetyloxy-6-[(3R,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid
• CAS: 103963-39-9
• 化学式: C₃₄H₅₀O₆
• 分子量: 554.8
• InChiKey: RXLRLJSRXDHQCH-ASNKJFCVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  40
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  89.9
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• INDUSTRIAL SCALE PROCESS OF CULTIVATING GANODERMA LUCIDUM MYCELIUM
  申请人：Double Crane Biotechnology Co. Ltd

  公开号：EP2997127B1

  公开（公告）日：2018-12-05
• Therapeutic Composition for Treating Cancers
  申请人：Double Crane Biotechnology Co., LTD

  公开号：US20140357604A1

  公开（公告）日：2014-12-04

  Disclosed herein is a composition that includes a novel combination of triterpenoids for the treatment or prophylaxis of a cancer. The triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS). The composition is suitable for the treatment or prophylaxis of colon cancer, hepatic cancer, breast cancer, lung cancer or leukemia.
• US9198922B2
  申请人：——

  公开号：US9198922B2

  公开（公告）日：2015-12-01
• US9820443B2
  申请人：——

  公开号：US9820443B2

  公开（公告）日：2017-11-21
• [EN] PROCESS FOR PREPARING DELTA-7,9(11) STEROIDS FROM GANODERMA LUCIDUM AND ANALOGS THEREOF<br/>[FR] PROCÉDÉ DE PRÉPARATION DE STÉROÏDES DELTA-7,9(11) À PARTIR DE GANODERMA LUCIDUM ET D'ANALOGUES DE CEUX-CI
  申请人：UNIV INDIANA RES & TECH CORP

  公开号：WO2012044817A2

  公开（公告）日：2012-04-05

  Processes for preparing lanostane triterpenes from the medicinal mushroom Ganoderma lucidum, and related compounds are described. Compounds, compositions, and methods for treating cancer are also described.