(8CI,9CI)-噻唑并[4,5-f]喹啉 | 233-75-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: (8CI,9CI)-噻唑并[4,5-f]喹啉
• 英文名称: Thiazolochinolin
• 英文别名: thiazolo[4,5-f]quinoline；Thiazolo[4,5-f]quinoline；[1,3]thiazolo[4,5-f]quinoline
• CAS: 233-75-0
• 化学式: C₁₀H₆N₂S
• mdl: MFCD18451410
• 分子量: 186.237
• InChiKey: LINNRIABMSURHW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2934999090

反应信息

• 作为产物：
  描述：

  5-isothiocyanatoquinoline 在 indium sulfate 作用下， 以 氯苯 为溶剂， 反应 5.0h， 以93%的产率得到(8CI,9CI)-噻唑并[4,5-f]喹啉
  参考文献：
  名称：

  一种聚碳酸酯抗高温降解剂的制备方法及一种聚碳酸酯组合物

  摘要：

  本发明提供了一种聚碳酸酯抗高温降解剂的制备方法及一种聚碳酸酯组合物，采用铟催化剂制备的抗高温降解剂的结构通式如下：，本发明制备方法简单、操作方便，并且产物易于提纯、收率高，可避免在聚碳酸酯组合物中引入杂质；该物质在空气氛围及高温条件下具有良好的抗高温降解能力，并且有利于节省聚碳酸酯组合物的生产成本。

  公开号：

  CN114516848A

文献信息

• [DE] TRICYCLISCHE HETEROAROMATISCHE VERBINDUNGEN<br/>[EN] TRICYCLIC HETEROAROMATIC COMPOUNDS<br/>[FR] COMPOSES HETEROAROMATIQUES TRICYCLIQUES
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2004089950A1

  公开（公告）日：2004-10-21

  Die Erfindung betrifft tricyclische heteroaromatische Verbindungen der allgemeinen Formel (I) und ihre Salze wobei die Strukturelemente X, Y, A, R1 und R2 in der Beschreibung definiert sind. Weiter betrifft die Erfindung die Herstellung dieser Verbindungen und ihre Verwendung als Arzneimittel, insbesondere als Schmerzmittel.

  本发明涉及通式（I）的三环杂环芳香化合物及其盐，其中描述了结构元素X、Y、A、R1和R2。本发明还涉及这些化合物的制备方法以及它们作为药物的用途，特别是作为止痛药。
• Tricyclic heteroaromatic compounds
  申请人：Boehringer Ingelheim International GmbH

  公开号：US20040214833A1

  公开（公告）日：2004-10-28

  The invention relates to tricyclic heteroaromatic compounds of general formula (I) and the salts thereof 1 wherein the structural elements X, Y, A, R 1 and R 2 are defined in the specification. The invention also relates to the preparation of these compounds and their use as pharmaceutical compositions, particularly as analgesics.

  本发明涉及通式（I）的三环杂芳化合物及其盐，其中结构元素X，Y，A，R1和R2在说明书中定义。本发明还涉及这些化合物的制备以及它们作为药物组合物的用途，特别是作为镇痛剂。
• Luminescent compositions and applications thereof
  申请人：THE PENN STATE RESEARCH FOUNDATION

  公开号：US10648917B2

  公开（公告）日：2020-05-12

  In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing includes disposing a fluorophore in a biological environment, wherein the fluorophore includes a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further includes exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, includes hydrogen ions, halide ions, and/or halogens.

  在一个方面，本文描述了传感方法。在一些实施例中，传感方法包括在生物环境中放置荧光团，其中荧光团包括二氧吡啶环（DPR）或噻唑吡啶酸（TPA）。该方法还包括将生物环境暴露于电磁辐射中，电磁辐射的波长与荧光团的激发波长相对应，检测荧光团发出的光，并将荧光团发出的光与生物环境中分析物的存在或不存在相关联，分析物的量超过最小检测阈值。分析物的存在可增加或减少荧光团发出的光量。被分析物的存在还可能移动峰值发射波长或改变荧光团的荧光寿命。在某些实施方案中，分析物包括氢离子、卤化物离子和/或卤素。
• Luminescent Compositions And Applications Thereof
  申请人：THE PENN STATE RESEARCH FOUNDATON

  公开号：US20180088053A1

  公开（公告）日：2018-03-29

  In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing comprises disposing a fluorophore in a biological environment, wherein the fluorophore comprises a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further comprises exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, comprises hydrogen ions, halide ions, and/or halogens.
• [EN] LUMINESCENT COMPOSITIONS AND APPLICATIONS THEREOF<br/>[FR] COMPOSITIONS LUMINESCENTES ET LEURS APPLICATIONS
  申请人：PENN STATE RES FOUND

  公开号：WO2016164437A1

  公开（公告）日：2016-10-13

  In one aspect, methods of sensing are described herein. In some embodiments, a method of sensing comprises disposing a fluorophore in a biological environment, wherein the fluorophore comprises a dioxo-pyridine ring (DPR) or a thiazolopyridine acid (TPA). The method further comprises exposing the biological environment to electromagnetic radiation having a wavelength corresponding to an excitation wavelength of the fluorophore, detecting light emitted by the fluorophore, and correlating the light emitted by the fluorophore to a presence or absence of an analyte within the biological environment in an amount above a minimum detection threshold. The presence of the analyte can increase or decrease the amount of light emitted by the fluorophore. The presence of the analyte may also shift the peak emission wavelength or alter the fluorescence lifetime of the fluorophore. The analyte, in some embodiments, comprises hydrogen ions, halide ions, and/or halogens.