2,5,7,8-tetramethyl-(2R-(4R,8R,12-trimethyltridecyl)-chroman-6-yloxy) hexanoic acid | 261929-55-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2,5,7,8-tetramethyl-(2R-(4R,8R,12-trimethyltridecyl)-chroman-6-yloxy) hexanoic acid
• 英文别名: 6-[[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]hexanoic acid
• CAS: 261929-55-9
• 化学式: C₃₅H₆₀O₄
• 分子量: 544.859
• InChiKey: KTOZBOUYSBMHFF-DOBRQBTGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.6
• 重原子数：
  39
• 可旋转键数：
  19
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SINGLE-STRANDED OLIGONUCLEOTIDE
  申请人：NISSAN CHEMICAL CORPORATION

  公开号：US20210254055A1

  公开（公告）日：2021-08-19

  The invention provides a single-stranded oligonucleotide represented by the formula (I), wherein X and Y hybridize by a first nucleotide sequence portion and a second nucleotide sequence portion. X is composed of 7 to 100 nucleotides, contains at least one modified-nucleotide, and has a first nucleotide sequence capable of hybridizing with a second oligonucleotide. Y is composed of 4 to 100 nucleotides, enables hybridization with the above-mentioned first oligonucleotide, and has a second nucleotide sequence containing at least one ribonucleotide. At least one of the nucleotide sequences X, Xz and Y has an antisense sequence capable of hybridizing with a target RNA. At least one of L, Lx and Ly is a linking group that contains a non-nucleotide structure.