5-(dithiolan-3-yl)-N-(4-methylphenyl)pentanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二硫杂环戊烷
• 英文名称: 5-(dithiolan-3-yl)-N-(4-methylphenyl)pentanamide
• 化学式: C₁₅H₂₁NOS₂
• 分子量: 295.5
• InChiKey: WXQCKIDDPGALPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  79.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Lipoyl Compounds And Their Use for Treating Ischemic Injury
  申请人：Baguisi Alexander B.

  公开号：US20130237483A1

  公开（公告）日：2013-09-12

  The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (la) or compositions comprising compounds of Structural Formulas (I) and (la), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed.
• LIPOYL COMPOUNDS AND METHODS FOR TREATING ISCHEMIC INJURY
  申请人：Ischemix LLC

  公开号：US20150065564A1

  公开（公告）日：2015-03-05

  The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (Ia) or compositions comprising compounds of Structural Formulas (I) and (Ia), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed.
• US8815937B2
  申请人：——

  公开号：US8815937B2

  公开（公告）日：2014-08-26
• US9359325B2
  申请人：——

  公开号：US9359325B2

  公开（公告）日：2016-06-07