1,1-二乙氧基十二烷 | 53405-98-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1,1-二乙氧基十二烷
• 英文名称: 1,1-diethoxydodecane
• CAS: 53405-98-4
• 化学式: C₁₆H₃₄O₂
• 分子量: 258.445
• InChiKey: CHURJRSXCYIYQX-UHFFFAOYSA-N

物化性质

• LogP：
  6.117 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,1-二乙氧基十二烷 在 三乙基硅基三氟甲磺酸酯 、 sodium hexamethyldisilazane 、 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 生成 月桂酸乙酯
  参考文献：
  名称：

  缩醛直接转变为具有高区域选择性酯由邻，P -acetals †

  摘要：

  O，O-乙缩醛通过以下方法直接转化为酯的新方法Ø，P -acetal开发了中间体。发生不对称环状缩醛的区域选择性裂解，以单一异构体形式得到更拥挤的酯。

  DOI：

  10.1039/c1ob05687e
• 作为产物：
  描述：

  十二醛 、 乙醇 在 camphor-10-sulfonic acid 作用下， 以 二氯甲烷 为溶剂， 生成 1,1-二乙氧基十二烷
  参考文献：
  名称：

  缩醛直接转变为具有高区域选择性酯由邻，P -acetals †

  摘要：

  O，O-乙缩醛通过以下方法直接转化为酯的新方法Ø，P -acetal开发了中间体。发生不对称环状缩醛的区域选择性裂解，以单一异构体形式得到更拥挤的酯。

  DOI：

  10.1039/c1ob05687e
• 作为试剂：
  描述：

  乙缩醛 在 6C₇₂H₁₁₂O₈*8H₂O 、 1,1-二乙氧基十二烷 作用下， 反应 1.0h， 生成 乙醛
  参考文献：
  名称：

  Hexameric Resorcinarene Capsule is a Brønsted Acid: Investigation and Application to Synthesis and Catalysis

  摘要：

  Molecular capsules have attracted interest as simple enzyme mimetics and several examples of catalytic transformations in water-soluble metal ligand based systems have been reported. This is not the case for hydrogen-bond based molecular capsules, which in contrast can be employed in organic solvents. We describe herein our investigations of such a system: The resorcin[4]arene hexamer is one of the largest hydrogen bond-based self-assembled capsules and has been studied intensively due to its ready availability. We present evidence that the capsule acts as a reasonably strong Bronsted acid (pK(a) approximately 5.5-6). This finding explains the capsule's high affinity toward tertiary amines that are protonated and therefore encounter cation-pi interactions inside the cavity. We were able to translate this finding into a first synthetic application: A highly substrate-selective Wittig reaction. We also report that this property renders the capsule an efficient enzyme-like catalyst for substrate selective diethyl acetal hydrolysis.

  DOI：

  10.1021/ja4080375

文献信息

• Pyridinium poly(hydrogen fluoride)-assisted cleavage of acetals and ketals
  作者：Yutaka Watanabe、Youko Kiyosawa、Akiko Tatsukawa、Minoru Hayashi

  DOI：10.1016/s0040-4039(01)00808-5

  日期：2001.7

  Acetals, including ketals, were smoothly cleaved by the action of pyridinium poly(hydrogen fluoride) without addition of water or an alcohol in an anhydrous solvent.

  在无水溶剂中不加水或醇的情况下，缩醛（包括缩酮）在吡啶鎓聚（氟化氢）的作用下被平滑地裂解。
• SYNTHETIC NAVEL ORANGEWORM PHEROMONE COMPOSITION AND METHODS RELATING TO PRODUCTION OF SAME
  申请人：Thompson Andrew

  公开号：US20100099920A1

  公开（公告）日：2010-04-22

  One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

  本发明的一个或多个实施例涉及合成方法，用于制备包括脐橙蠹蛾信息素在内的鳞翅目昆虫信息素。这些合成方法涉及新颖、高效和环境友好的步骤和程序。
• An Acetal Acylation Methodology for Producing Diversity of Trihalomethyl- 1,3‑dielectrophiles and 1,2-Azole Derivatives
  作者：Valéria Bareño、Daiane Santos、Leandro Frigo、Debora de Mello、Juliana Malavolta、Rogerio Blanco、Lucas Pizzuti、Darlene Flores、Alex Flores

  DOI：10.21577/0103-5053.20190160

  日期：——

  A series of functionalized 1,1,1-trihalo-4-methoxy-3-alken-2-ones [CX3C(O)CR1=CROMe, where X = F or Cl; R = n-heptyl, n-octyl, n-nonyl, n-decyl, n-undecyl, n-tridecyl, (CH2)(2)CH=C(Me)(2), (CH2)(2)Ph, (CH2)(2)-(4-HOC6H4), (CH2)(2)-(4-MeOC6H4), (CH2)(2)CO2Me, (CH2)(3)CO2Me, CH(SMe)CH3, CH2(2-MeOC6H4), and R-1 = H, and R = H and R-1 = n-decyl] were synthesized from respective alkyl methyl ketones or aldehyde via acetal acylation using trifluoroacetic anhydride and trichloroacetyl chloride. 1,1,1-Trihalo-4-methoxy-3-alken-2-ones with acid-compatible substituents were easily hydrolyzed to respective trihalomethyl-1,3-diketones. The 1,1,1-trihalo-4-methoxy-3-alken-2-ones and/or respective trihalomethyl-1,3-diketones were reacted regiospecifically with hydroxylamine hydrochloride, leading to isoxazole derivatives, and with hydrazines, leading to respective 1H-pyrazole derivatives. The structures of all compounds were assigned based on nuclear magnetic resonance (NMR) and mass spectrometric data. This method represents an efficient pathway for the regioselective trihaloacetylation of asymmetrically substituted alkyl methyl ketones and highly self-condensing aldehydes. Moreover, this approach allows the introduction of biologically recognizable moieties, such as those from levulinic acid, sulcatone (prenyl), benzylacetone, anisylacetone, and raspberry ketone, as synthetic molecular targets.
• JPH093087A
  申请人：——

  公开号：JPH093087A

  公开（公告）日：1997-01-07
• SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER
  申请人：Sumitomo Chemical Company, Limited

  公开号：US20130072648A1

  公开（公告）日：2013-03-21

  A solid catalyst for olefin polymerization and a process for producing an olefin polymer are provided. The polymer has a small content of a component which is dissolved out into a low temperature organic solvent, such as a low-molecular weight component and an amorphous component. The solid catalyst is obtained by bringing a solid catalyst component for olefin polymerization containing a titanium atom, a magnesium atom, a halogen atom, and an aliphatic carboxylate; an organoaluminum compound; and a compound represented by formula (I) into contact with each other: wherein R 1 is a hydrocarbyl group having 1 to 10 carbon atoms, R 2 is a hydrogen atom, a halogen atom or a hydrocarbyl group having 1 to 16 carbon atoms, and the R 1 the R 2 groups are independently the same or different, and the respective R 1 groups and R 2 groups may be joined with each other to form a ring.