1,2,4-三甲基环己烯 | 90769-69-0

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 中文名称: 1,2,4-三甲基环己烯
• 英文名称: 1,2,4-trimethylcyclohex-1-ene
• 英文别名: (+/-)-1,2,4-trimethyl-cyclohexene；1,2,4-trimethyl-cyclohexene；(+/-)-1,2,4-Trimethyl-cyclohexen；1,2,4-Trimethyl-cyclohexen；1,2,4-trimethylcyclohexene
• CAS: 90769-69-0
• 化学式: C₉H₁₆
• mdl: MFCD07780513
• 分子量: 124.226
• InChiKey: BNFMZPKOXZHOMZ-UHFFFAOYSA-N

物化性质

• 沸点：
  152 °C
• 密度：
  0.8275 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.777
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2,4-三甲基环己烯 在 chromium corundum 作用下， 生成 1,2,4-三甲基苯
  参考文献：
  名称：

  SYNTHESIS OF THE THREE TRIMETHYL- AND CERTAIN OTHER POLYALKYL-BENZENES

  摘要：

  DOI：

  10.1021/jo01152a003
• 作为产物：
  描述：

  1,2,4-trimethyl-cyclohexa-1,4-diene 生成 1,2,4-三甲基环己烯
  参考文献：
  名称：

  Genetic and Biogeographic Relationships of the Invasive Round (Neogobius melanostomus) and Tubenose (Proterorhinus marmoratus) Gobies in the Great Lakes Versus Eurasian Populations

  摘要：

  Population genetic structure and systematic relationships were investigated for two exotic fishes introduced to the Great Lakes in 1990, the round goby Neogobius melanostomus and the tubenose goby Proterorhinus marmoratus, using DNA sequences from the left domain of the mitochondrial DNA control region. Samples of round gobies were compared from different sites in the Great Lakes, an introduced population from the Gulf of Gdansk in Poland, and a native population from the northern Black Sea. The round goby was characterized by, relatively high genetic variability, and 17 haplotypes were identified from 64 individuals. Levels of genetic variation for the round goby were similar in the invasive and native sampling sites, suggesting relatively large founding populations and lack of bottlenecks. The northern Black Sea was eliminated as a probable founding source for both the Great Lakes and the exotic population in Poland. Substitutions in the left domain of the control region revealed significant differences among samples from the Great Lakes and Eurasia, and between Lakes Erie and St. Clair, suggesting non-random mating. No variation was detected in the tubenose goby population in the Great Lakes, which has been less successful in terms of spread and population growth. A molecular clock calibration suggested that the genera Neogobius and Proterorhinus diverged about 5.2 +/- 1.0 million years ago, apparently separating from a common ancestor shared with Gobius during the isolation of the Paratethys basin from the Mediterranean Tethys Sea.

  DOI：

  10.1016/s0380-1330(01)70642-9

文献信息

• Unsaturated Aldehydes as Alkene Equivalents in the Diels–Alder Reaction
  作者：Esben Taarning、Robert Madsen

  DOI：10.1002/chem.200800003

  日期：2008.6.20

  A one-pot procedure is described for using alpha,beta-unsaturated aldehydes as olefin equivalents in the Diels-Alder reaction. The method combines the normal electron demand cycloaddition with aldehyde dienophiles and the rhodium-catalyzed decarbonylation of aldehydes to afford cyclohexenes with no electron-withdrawing substituents. In this way, the aldehyde group serves as a traceless control element

  描述了一种一锅法，该方法用于在Diels-Alder反应中使用α，β-不饱和醛作为烯烃当量。该方法将正常的电子需求环加成反应与醛二烯亲和剂和铑催化的醛脱羰反应结合在一起，得到不具有吸电子取代基的环己烯。以这种方式，醛基用作指导环加成反应的无痕控制元素。在催化量的三氟化硼醚化物的存在下，在二甘醇二甲醚溶液中进行Diels-Alder反应。随后路易斯酸的淬灭，添加0.3％的[Rh（dppp）2 Cl]并加热至回流实现了随后的脱羰作用，得到了环己烯产物。在这些条件下，丙烯醛，巴豆醛和肉桂醛已与多种1，3-二烯可提供环己烯的总收率在53％到88％之间。在这些转化中，这三种醛分别相当于乙烯，丙烯和苯乙烯。
• Factors influencing conformational preferences in cyclohexenes
  作者：Joseph B. Lambert、Dale E. Marko

  DOI：10.1021/ja00312a030

  日期：1985.12
• WO2007/13469
  申请人：——

  公开号：——

  公开（公告）日：——
• Genetic and Biogeographic Relationships of the Invasive Round (Neogobius melanostomus) and Tubenose (Proterorhinus marmoratus) Gobies in the Great Lakes Versus Eurasian Populations
  作者：Alison K. Dillon、Carol A. Stepien

  DOI：10.1016/s0380-1330(01)70642-9

  日期：2001.1

  Population genetic structure and systematic relationships were investigated for two exotic fishes introduced to the Great Lakes in 1990, the round goby Neogobius melanostomus and the tubenose goby Proterorhinus marmoratus, using DNA sequences from the left domain of the mitochondrial DNA control region. Samples of round gobies were compared from different sites in the Great Lakes, an introduced population from the Gulf of Gdansk in Poland, and a native population from the northern Black Sea. The round goby was characterized by, relatively high genetic variability, and 17 haplotypes were identified from 64 individuals. Levels of genetic variation for the round goby were similar in the invasive and native sampling sites, suggesting relatively large founding populations and lack of bottlenecks. The northern Black Sea was eliminated as a probable founding source for both the Great Lakes and the exotic population in Poland. Substitutions in the left domain of the control region revealed significant differences among samples from the Great Lakes and Eurasia, and between Lakes Erie and St. Clair, suggesting non-random mating. No variation was detected in the tubenose goby population in the Great Lakes, which has been less successful in terms of spread and population growth. A molecular clock calibration suggested that the genera Neogobius and Proterorhinus diverged about 5.2 +/- 1.0 million years ago, apparently separating from a common ancestor shared with Gobius during the isolation of the Paratethys basin from the Mediterranean Tethys Sea.
• SYNTHESIS OF THE THREE TRIMETHYL- AND CERTAIN OTHER POLYALKYL-BENZENES
  作者：J.E. NICKELS、W. HEINTZELMAN

  DOI：10.1021/jo01152a003

  日期：1950.11