毒理性
◉ 母乳喂养期间使用概述：辅酶Q10（泛醌）是日常饮食的正常组成部分，并且可以在体内内生合成。它是人类母乳的正常成分，但是早产儿母亲的母乳中辅酶Q10的水平略低。辅酶Q10没有特定的与哺乳相关的用途，并且没有关于补充哺乳母亲或婴儿的安全性和有效性的数据。辅酶Q10补充剂通常耐受性良好，只会有偶尔的轻微副作用。
膳食补充剂不需要美国食品药品监督管理局的广泛市场前批准。制造商负责确保安全性，但在市场营销前不需要证明膳食补充剂的安全性和有效性。膳食补充剂可能含有多种成分，标签上标注的成分或其数量与实际成分或数量之间经常存在差异。制造商可以与独立组织签订合同，以验证产品的质量或其成分，但这并不证明产品的安全或有效性。由于上述问题，对某一产品的临床测试结果可能不适用于其他产品。关于膳食补充剂的更详细信息可以在LactMed网站的其它地方找到。
◉ 对母乳喂养婴儿的影响：截至修订日期，没有找到相关的已发布信息。
◉ 对泌乳和母乳的影响：截至修订日期，没有找到相关的已发布信息。
◉ Summary of Use during Lactation:Coenzyme Q10 (ubiquinone) is a normal part of the diet, and is also endogenously synthesized. It is a normal component of human milk, but milk levels are slightly low in the breastmilk of mothers with preterm infants. Coenzyme Q10 has no specific lactation-related uses and no data exist on the safety and efficacy of supplementation in nursing mothers or infants. Coenzyme Q10 supplements are usually well tolerated with only infrequent, minor side effects.
Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.
◉ Effects in Breastfed Infants:Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk:Relevant published information was not found as of the revision date.
来源:Drugs and Lactation Database (LactMed)
