1-(4-氯苯基)-4-二甲基氨基-2,3-二甲基丁烷-2-醇盐酸盐 | 1215-83-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-(4-氯苯基)-4-二甲基氨基-2,3-二甲基丁烷-2-醇盐酸盐
• 中文别名: 酸氯丁替诺 标准品
• 英文名称: 1-(4-Chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol;hydron;chloride
• 英文别名: 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol;hydron;chloride
• CAS: 1215-83-4
• 化学式: C14H23Cl2NO
• 分子量: 292.2
• InChiKey: ZMROYCGIWPNZNJ-UHFFFAOYSA-N

物化性质

• 熔点：
  169-170°

计算性质

• 辛醇/水分配系数(LogP)：
  3.0
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  23.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2922199090

文献信息

• Sweetener compositions and uses thereof
  申请人：AJINOMOTO CO. INC

  公开号：US20040105928A1

  公开（公告）日：2004-06-03

  The present invention provides compositions containing one or more aspartyl dipeptide derivatives represented by formulas (1) and/or (2) mixed with another high intensity sweetner, such Aspartame, sugar, sugar alcohol, and oligosaccharide; food, beverages, and/or medicinal products containing these compositions, methods of using the compositions to impart sweetness in food, beverages, and/or medicinal products to impart sweetness or suppress a bitter taste; and methods of making the compositions and products.

  本发明提供了一种含有一个或多个由式(1)和/或式(2)表示的天冬氨酰二肽衍生物与另一种高强度甜味剂混合的组合物；含有这些组合物的食品、饮料和/或药品；使用这些组合物在食品、饮料和/或药品中赋予甜味或抑制苦味的方法；以及制备这些组合物和产品的方法。其中，另一种高强度甜味剂可以是阿斯巴甜、糖、糖醇和寡糖。
• Type II Cubic Liquid Crystal Composition
  申请人：Hatoh Masakatsu

  公开号：US20080113923A1

  公开（公告）日：2008-05-15

  A cubic liquid crystal composition comprising at least one amphiphilic compound having the following general formula (1) and having an IV/OV value of 0.65 to 0.95, and water or an aqueous medium: wherein R represents a hydrophilic group; X and Y each independently represent a hydrogen atom or together form an oxygen atom; n is an integer of 0 to 4; and m is an integer of 0 to 3.

  一种立方液晶组合物，包括至少一种具有以下通式（1）并具有0.65至0.95的IV/OV值的两性化合物和水或水性介质：其中R代表亲水基团；X和Y各自独立地表示氢原子或一起形成氧原子；n为0至4的整数；m为0至3的整数。
• Medicated plasters
  申请人：NITTO DENKO CORPORATION

  公开号：EP0387751A2

  公开（公告）日：1990-09-19

  Medicated plasters composed of a flexible support and a pressure-sensitive adhesive layer laminated thereon, in which said pressure-sensitive adhesive layer has an exposed surface with pH of 7 or higher and contains one of the following three components: (i) a basic physiologically active agent and an acidic substance, (ii) a salt of a basic physiologically active agent and a basic substance, and (iii) a basic physiolosically active agent and a salt of a basic physiolosically active agent.

  药用膏药，由柔性支架和层压在其上的压敏胶层组成，其中所述压敏胶层的外露表面 pH 值为 7 或更高，并含有以下三种成分之一： (i) 碱性生理活性剂和酸性物质、 (ii) 碱性生理活性剂和碱性物质的盐，以及 (iii) 碱性生理活性剂和碱性生理活性剂的盐。
• Process to prepare coated particles
  申请人：TAISHO PHARMACEUTICAL CO. LTD

  公开号：EP0413865A1

  公开（公告）日：1991-02-27

  A method of producing a fine coated pharmaceutical preparation comprises cooling fine liquid droplets composed of a liquid medium, a drug dissolved or suspended in the liquid medium, and as required, a binder, to a temperature not higher than the freezing point of the liquid medium to form frozen particles aof the drug and, as required, the binder; adjusting the particle sizes of the fine frozen particles; mixing the fine frozen particles with a fine powder of a coating material having a particle diameter less than said particles at a temperature above the freezing point of the liquid medium to cause the fine powder of the coating material to adhere to the surface of said particles; and then removing the liquid medium from the resulting coated particles.

  一种生产精细包衣药物制剂的方法，包括将由液体介质、溶解或悬浮在液体介质中的药物以及所需的粘合剂组成的细液滴冷却到不高于液体介质冰点的温度，以形成药物以及所需的粘合剂的冷冻颗粒；调整细冷冻颗粒的粒径；在高于液体介质冰点的温度下，将微冻颗粒与颗粒直径小于所述颗粒的包衣材料细粉混合，使包衣材料细粉附着在所述颗粒表面；然后从得到的包衣颗粒中去除液体介质。
• CAPSULE
  申请人：NIPPON SHINYAKU COMPANY, LIMITED

  公开号：EP0580861A1

  公开（公告）日：1994-02-02

  A prolonged-action capsule excellent in adhesion, stability, etc., in the digestive tract. The capsule comprises a polymer excellent in initial adhesion and another polymer excellent in shape retention, both of which are dispersed in a liquid substance, and a physiologically active substance dispersed or dissolved in a liquid substance, and contains water in an amount of 2 % or less as a whole.

  一种在消化道中具有良好粘附性和稳定性的长效胶囊。该胶囊由一种初始粘附性极佳的聚合物和另一种形状保持性极佳的聚合物组成，这两种聚合物都分散在一种液体物质中，还包括一种分散或溶解在液体物质中的生理活性物质，其整体含水量不超过 2%。