樟脑对氯苯酚 | 8003-18-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 樟脑对氯苯酚
• 英文名称: Parachlorophenol, Camphorated
• 英文别名: 4-chlorophenol;1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
• CAS: 8003-18-7
• 化学式: C16H21ClO2
• 分子量: 280.79
• InChiKey: GMDACCYEPJRFLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.45
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Liquid polymer composition, and method of use
  申请人：YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM

  公开号：EP0404558A1

  公开（公告）日：1990-12-27

  The invention relates to liquid methacrylic acid (co)polymer compositions that contain a release adjusting agent and a pharmacological agent. The compositions form a solid film upon drying, and are capable of accomplishing the sustained release of the pharmacological agent such as to permit its use in the treatment or prevention of dental or dermatological conditions.

  本发明涉及含有释放调节剂和药剂的液态甲基丙烯酸（共）聚合物组合物。这种组合物在干燥后形成一层固体薄膜，能够实现药剂的持续释放，从而可用于治疗或预防牙科或皮肤病。
• ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE AND ULTRASONIC DRUG DELIVERY METHOD FOR DENTAL USE
  申请人：Japan Health Sciences Foundation

  公开号：EP2514387A1

  公开（公告）日：2012-10-24

  A dental ultrasonic drug delivery system capable of accurately cleaning the inside of root canals and killing bacteria in dentin tubules is provided. The dental ultrasonic drug delivery system delivers a drug to a target using an ultrasonic delivery device 800. The drug is delivered in a mixed state with nanobubbles. A dental therapeutic probe for applying ultrasound is attached to the ultrasonic delivery device 800. The dental therapeutic probe is selected from: (1) a root canal insertion probe 100 which is configured to be inserted into a root canal and causes ultrasound to propagate in the root canal; (2) a dental caries therapeutic probe which causes ultrasound to propagate in a dental caries portion; (3) a periodontal disease therapeutic probe which applies ultrasound to a periodontal disease portion; and (4) a hyperesthesia therapeutic probe which applies ultrasound to hyperesthesia portion.

  本发明提供了一种牙科超声波给药系统，能够准确清洁根管内部并杀死牙本质小管中的细菌。牙科超声波给药系统使用超声波给药装置 800 将药物输送到目标物。药物以与纳米气泡混合的状态输送。用于应用超声波的牙科治疗探针连接到超声波给药装置 800 上。牙科治疗探针选自：(1) 根管插入探针 100，其配置为插入根管并使超声波在根管中传播；(2) 龋齿治疗探针，其使超声波在龋齿部分传播；(3) 牙周疾病治疗探针，其对牙周疾病部分施加超声波；以及 (4) 过度兴奋治疗探针，其对过度兴奋部分施加超声波。
• Methods and apparatus for stabilization of surfaces
  申请人：Polylast Systems, LLC

  公开号：US10309070B2

  公开（公告）日：2019-06-04

  Various embodiments provide surface compositions and methods for porous, flexible, and durable surfaces that may stabilize native soil, provide substantially uniform drainage of moisture, and provide a barrier between the native soil, vegetation, and other compositions disposed over the surface composition, such as sand and/or soil. The compositions and methods may comprise utilizing a liquid coating composition, liquid binder, and/or antimicrobial composition in combination with a particulate material configured to provide a desired pore size, elasticity, compression, and/or stability to the surface composition. Various embodiments of the surface composition may form a prefabricated flexible bunker liner for application to the native soil in a golf course bunker beneath sand.

  各种实施方案提供了用于多孔、柔韧和耐用表面的表面组合物和方法，这些表面组合物和方法可以稳定原生土壤，提供基本均匀的水分排放，并在原生土壤、植被和放置在表面组合物上的其他组合物（如沙子和/或土壤）之间提供屏障。这些组合物和方法可包括利用液体涂层组合物、液体粘结剂和/或抗菌组合物与颗粒材料相结合，使表面组合物具有所需的孔径、弹性、压缩性和/或稳定性。表面组合物的各种实施方案可形成预制的柔性沙坑衬垫，用于高尔夫球场沙坑中沙下的原生土壤。
• Oral care compositions
  申请人：——

  公开号：US20030007937A1

  公开（公告）日：2003-01-09

  Disclosed are stable oral care compositions, preferably confectionery compositions, which provide enhanced oral malodor benefits combined with one or more additional oral care benefits, wherein the compositions comprise: (i) a polyphosphate material with an average anion chain length of 3 or greater; (ii) greater than about 10 ppm of a first metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (iii) greater than about 10 ppm of a second metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11,12,14, 16 of the periodic table; and (iv) a pharmaceutically acceptable carrier, wherein the molar ratio of polyphosphate anion to the total level of first and second metal cation combined is in the range of from about 10:1 to about 1:1 and wherein the molar ratio of the first metal cation to the second metal cation is in the range of from about 50:1 to about 1:50.

  所公开的是稳定的口腔护理组合物，最好是糖果组合物，它提供增强的口腔恶臭益处，并结合一种或多种额外的口腔护理益处，其中组合物包括 (i) 平均阴离子链长度大于等于 3 的聚磷酸盐材料； (ii) 大于约 10ppm 的选自元素周期表中第 5、6、7、8、9、10、11、12、 14、16 族金属的第一金属阳离子； (iii) 大于约 10 ppm 的选自元素周期表第 5、6、7、8、9、10、11、12、14、 16 族金属的第二金属阳离子；以及 (iv) 医药上可接受的载体、 其中聚磷酸盐阴离子与第一和第二金属阳离子总含量的摩尔比在约 10:1 至约 1:1 的范围内，第一金属阳离子与第二金属阳离子的摩尔比在约 50:1 至约 1:50 的范围内。
• Confectionery compositions
  申请人：The Procter & Gamble Company

  公开号：US20030007997A1

  公开（公告）日：2003-01-09

  Disclosed are stable portable oral care confectionery compositions which provide enhanced oral malodour benefits combined with enhanced anti-calculus benefits, wherein the confectionery compositions comprise: (i) a polyphosphate material with an average anion chain length of greater than or equal to 3; (ii) greater than about 10 ppm of a metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (iii) less than about 10% water; and (iv) a suitable confectionery carrier material wherein the ratio of polyphosphate anion to metal cation is in the range of from about 10:1 to about 1:1.

  本发明公开了稳定的便携式口腔护理糖果组合物，该组合物具有增强的口腔恶臭益处和增强的抗结石益处，其中糖果组合物包括 (i) 平均阴离子链长度大于或等于 3 的聚磷酸盐材料； (ii) 大于约 10ppm 的选自元素周期表第 5、6、7、8、9、10、11、12、14、 16 族金属的金属阳离子； (iii) 少于约 10%的水；以及 (iv) 一种合适的糖果载体材料 其中聚磷酸盐阴离子与金属阳离子的比例范围为约 10:1 至约 1:1。