樟脑苯酚 | 37262-59-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 樟脑苯酚
• 中文别名: 1H-吲哚-5-甲酰胺,N-(氨基亚氨基甲基)-1-甲基-
• 英文名称: Campho-phenique
• 英文别名: phenol;1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
• CAS: 37262-59-2；8002-06-0
• 化学式: C16H22O2
• 分子量: 246.34
• InChiKey: LKTOWUZQHJSGAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.79
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE AND ULTRASONIC DRUG DELIVERY METHOD FOR DENTAL USE
  申请人：Japan Health Sciences Foundation

  公开号：EP2514387A1

  公开（公告）日：2012-10-24

  A dental ultrasonic drug delivery system capable of accurately cleaning the inside of root canals and killing bacteria in dentin tubules is provided. The dental ultrasonic drug delivery system delivers a drug to a target using an ultrasonic delivery device 800. The drug is delivered in a mixed state with nanobubbles. A dental therapeutic probe for applying ultrasound is attached to the ultrasonic delivery device 800. The dental therapeutic probe is selected from: (1) a root canal insertion probe 100 which is configured to be inserted into a root canal and causes ultrasound to propagate in the root canal; (2) a dental caries therapeutic probe which causes ultrasound to propagate in a dental caries portion; (3) a periodontal disease therapeutic probe which applies ultrasound to a periodontal disease portion; and (4) a hyperesthesia therapeutic probe which applies ultrasound to hyperesthesia portion.

  本发明提供了一种牙科超声波给药系统，能够准确清洁根管内部并杀死牙本质小管中的细菌。牙科超声波给药系统使用超声波给药装置 800 将药物输送到目标物。药物以与纳米气泡混合的状态输送。用于应用超声波的牙科治疗探针连接到超声波给药装置 800 上。牙科治疗探针选自：(1) 根管插入探针 100，其配置为插入根管并使超声波在根管中传播；(2) 龋齿治疗探针，其使超声波在龋齿部分传播；(3) 牙周疾病治疗探针，其对牙周疾病部分施加超声波；以及 (4) 过度兴奋治疗探针，其对过度兴奋部分施加超声波。
• Skin oils consisting of oil-soluble constituents and w/o-emulsifiers having an hlb value of between 2 and 6 and optionally at least one standard additive, method for the production thereof and use of the same
  申请人：——

  公开号：US20040067206A1

  公开（公告）日：2004-04-08

  The invention relates to fatty skin oils containing at least one oil-soluble constituent, at least one O/W-emulsifier having and HLB value of between 2 and 6, preferably between 2 and 5, 9, and optionally at least one additive selected from ethereal oils, antioxidants, scented substances, preservatives, active ingredients, UV filters, vitamins, thickeners, and solubilisers. The invention also relates to the production of said oils and the use of the same as skin oils, especially as skin care oils, sport oils, massage oils or sun oils. Said skin oils can be applied to dry skin and especially lo wet skin, having a self-emulsifying action and the advantages related thereto, soaking easily into the skin without leaving an unwanted greasy film.

  本发明涉及含至少一种油溶性成分、至少一种 HLB 值介于 2 和 6 之间（最好介于 2 和 5、9 之间）的 O/W 型乳化剂以及可选的至少一种添加剂的脂肪护肤油，这些添加剂选自乙醇油、抗氧化剂、芳香物质、防腐剂、活性成分、紫外线过滤剂、维生素、增稠剂和增溶剂。本发明还涉及上述油类的生产和用作护肤油，特别是护肤油、运动油、按摩油或防晒油。所述护肤油可用于干性皮肤，尤其是湿性皮肤，具有自乳化作用和相关优点，很容易浸透皮肤，不会留下多余的油脂膜。
• Vesicle forming skin oils comprising w/o-emusifiers with an hydrophilic-lipophilic balance of 2-6, method for the production and the use thereof
  申请人：——

  公开号：US20040076652A1

  公开（公告）日：2004-04-22

  The invention relates to skin oils containing fat, containing one or more oil soluble components, one or more W/O emulsifiers with a hydrophilic-lipophilic balance of 2-6, preferably 5.9, one or more vesicle forming lipids and, optionally, one or more additives selected from etherical oils, antioxidants, perfumed materials, preservatives, active ingredients, UV filters, vitamins, consistency modulators and solubilizers. The invention also relates to the production and the use of said skin oil, particularly as a skin care oil, sport oil, massage oil or sun protection oil. Said skin oils can be applied on dry skin and particularly on wet skin. Said oil is self-emulsifying and spontaneously forms liposomes. Said oil also has the advantage as it can easily penetrate the skin without leaving a disturbing layer of fat thereon.

  本发明涉及含脂肪的护肤油，含有一种或多种油溶性成分、一种或多种亲水-亲油平衡度为 2-6（优选 5.9）的水包油型乳化剂、一种或多种形成囊泡的脂质，以及可选的一种或多种添加剂，这些添加剂选自醚油、抗氧化剂、香料、防腐剂、活性成分、紫外线过滤剂、维生素、稠度调节剂和增溶剂。本发明还涉及所述护肤油的生产和使用，特别是作为护肤油、运动油、按摩油或防晒油。所述护肤油可用于干性皮肤，尤其是湿性皮肤。所述护肤油具有自乳化性，可自发形成脂质体。此外，护肤油还具有易于渗透皮肤而不会在皮肤上留下脂肪层的优点。
• ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE
  申请人：National Center for Geriatrics and Gerontology

  公开号：EP2514387B1

  公开（公告）日：2018-03-21
• DENTAL ULTRASONIC DRUG DELIVERY SYSTEM AND DENTAL ULTRASONIC DRUG DELIVERY METHOD
  申请人：Nakashima Misako

  公开号：US20120270177A1

  公开（公告）日：2012-10-25

  A dental ultrasonic drug delivery system capable of accurately cleaning the inside of root canals and killing bacteria in dentin tubules is provided. The dental ultrasonic drug delivery system delivers a drug to a target using an ultrasonic delivery device 800 . The drug is delivered in a mixed state with nanobubbles. A dental therapeutic probe for applying ultrasound is attached to the ultrasonic delivery device 800 . The dental therapeutic probe is selected from: (1) a root canal insertion probe 100 which is configured to be inserted into a root canal and causes ultrasound to propagate in the root canal; (2) a dental caries therapeutic probe which causes ultrasound to propagate in a dental caries portion; (3) a periodontal disease therapeutic probe which applies ultrasound to a periodontal disease portion; and (4) a hyperesthesia therapeutic probe which applies ultrasound to hyperesthesia portion.