1-乙基-2-[(1-乙基喹啉-2-亚基)甲基]喹啉-1-鎓氯化物 | 2402-42-8

• 物质功能分类: 医药中间体 - 杂环化合物 - 喹啉类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 1-乙基-2-[(1-乙基喹啉-2-亚基)甲基]喹啉-1-鎓氯化物
• 英文名称: pseudoisocyanine chloride
• 英文别名: 1,1'-diethyl-2,2'-cyanine chloride；1,1'-diethyl-2,2'-quinocyanine chloride；NSC97374；(2Z)-1-ethyl-2-[(1-ethylquinolin-1-ium-2-yl)methylidene]quinoline;chloride
• CAS: 2402-42-8
• 化学式: C₂₃H₂₃N₂*Cl
• 分子量: 362.902
• InChiKey: MHQOURYMHSSLDM-UHFFFAOYSA-M

物化性质

• 熔点：
  215 °C

计算性质

• 辛醇/水分配系数(LogP)：
  2.05
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-[5-phenyl-2-[(Z)-2-[(Z)-[5-phenyl-3-(3-sulfopropyl)-1,3-benzoxazol-2-ylidene]methyl]but-1-enyl]-1,3-benzoxazol-3-ium-3-yl]propane-1-sulfonate 、 1-乙基-2-[(1-乙基喹啉-2-亚基)甲基]喹啉-1-鎓氯化物 以100%的产率得到
  参考文献：
  名称：

  FORMINA, L. V.;LYUBICH, M. S.;MONICH, N. V.;VOMPE, A. F.

  摘要：

  DOI：

文献信息

• FORMINA, L. V.;LYUBICH, M. S.;MONICH, N. V.;VOMPE, A. F.
  作者：FORMINA, L. V.、LYUBICH, M. S.、MONICH, N. V.、VOMPE, A. F.

  DOI：——

  日期：——
• Homeotropic and hybrid bulk alignment of lyotropic chromonic liquid crystals
  申请人：Lavrentovich Oleg D.

  公开号：US20090226639A1

  公开（公告）日：2009-09-10

  The invention provides a liquid crystal cell and method thereof. The cell comprises two opposed substrates and a surfactant-free lyotropic chromonic liquid crystals (LCLC) material disposed therebetween. By using an ammonium compound with LCLC or surface treatment on the substrates, the alignment of the LCLC material can be manipulated as a homeotropic bulk alignment; or a hybrid bulk alignment in which the LCLC alignment is changed from homeotropic bulk alignment in the vicinity of one substrate to planar alignment in the vicinity of another substrate. The cell can be used in biosensing, detection and amplification of ligands, optical devices, and photovoltaics etc.
• METHODS OF DETECTING BIOLOGICAL ACTIVITY, CELLULAR BEHAVIOR AND DRUG DELIVERY USING ENCAPSULATED POLYMETHINE AGGREGATES
  申请人：Nanohybrids

  公开号：US20180078659A1

  公开（公告）日：2018-03-22

  Presented herein are methods of using encapsulated J-aggregates of indocyanine green (ICG) as a ratiometric sensor of biological activity. Upon interaction with a biological phenomenon of interest, the encapsulated J-aggregates can be released and dissolved upon rupture, inducing a detectable hypsochromic shift in the absorption spectra and corresponding increase in fluorescence. Various imaging techniques can be employed to visualize this sensor including photoacoustic imaging, two-photon imaging, fluorescence imaging, near infrared imaging, and a variety of other optical or optics-based techniques. Additionally, if the J-aggregates of ICG are also encapsulated with drugs or therapeutic molecules, the ratiometric sensing using ICG can be used to confirm drug release and delivery.
• DYE AGGREGATES-CONTAINING NANOPARTICLES AND USES THEREOF
  申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

  公开号：US20210154335A1

  公开（公告）日：2021-05-27

  The present invention provides compositions relating to nanoparticles, such as nanocapsules, that selectively target cells associated with diseases or disorders (e.g., cancer cells). The present invention further relates to methods relating to the said nanoparticles for imaging, detection, and treatment of diseases or disorders in a subject. The present invention additionally provides kits that find use in the practice of the methods of the invention.
• US5086239A
  申请人：——

  公开号：US5086239A

  公开（公告）日：1992-02-04