12-脱氧佛波醇-13-癸酸酯 | 70278-05-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 12-脱氧佛波醇-13-癸酸酯
• 英文名称: 12-Deoxyphorbol-13-decanoate
• 英文别名: [(1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] decanoate
• CAS: 70278-05-6
• 化学式: C₃₀H₄₆O₆
• 分子量: 502.7
• InChiKey: WZNILJZDDKVACY-RPWXAJKISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  36
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Compositions and methods of antiallergic phorbol ester and phorbol derivatives as the main active ingredients from the seeds of aquilaria malaccensis
  申请人：WE-WIN APPLIED BIO-TECH CO., LTD.

  公开号：US10335445B2

  公开（公告）日：2019-07-02

  The present invention relates to phorbol esters from the seeds of Aquilaria malaccensis by a series of chromatographic processes, and compositions containing these congeners for the treatment of allergic responses.

  本发明涉及通过一系列色谱过程从马尾藻（Aquilaria malaccensis）种子中提取的植物醇酯，以及含有这些同系物的用于治疗过敏反应的组合物。
• COMPOSITIONS AND METHODS OF ANTIALLERGIC PHORBOL ESTER AND PHORBOL DERIVATIVES AS THE MAIN ACTIVE INGREDIENTS FROM THE SEEDS OF AQUILARIA MALACCENSIS
  申请人：WE-WIN APPLIED BIO-TECH CO., LTD.

  公开号：US20170266250A1

  公开（公告）日：2017-09-21

  The present invention relates to phorbol esters from the seeds of Aquilaria malaccensis by a series of chromatographic processes, and compositions containing these congeners for the treatment or prevention of allergic responses. Furthermore, compositions are provided which comprise these phorbol esters in combination with at least one to assess the effects for preventing or treating allergies.