氯化四苯砷 | 507-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 氯化四苯砷
• 中文别名: 四苯基氯化砷；四苯砷氯水合物
• 英文名称: tetraphenylarsonium chloride
• 英文别名: tetraphenylarsanium;chloride
• CAS: 507-28-8
• 化学式: C₂₄H₂₀As*Cl
• 分子量: 418.797
• InChiKey: NRZGVGVFPHPXEO-UHFFFAOYSA-M

物化性质

• 熔点：
  258-260 °C(lit.)
• 稳定性/保质期：
  按规格使用和贮存，不会发生分解，避免与氧化物接触。

计算性质

• 辛醇/水分配系数(LogP)：
  0.07
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 危险等级：
  6.1
• 危险品标志：
  T,N
• 危险类别码：
  R50/53,R23/25
• 危险品运输编号：
  UN 3465 6.1/PG 3
• WGK Germany：
  3
• RTECS号：
  CI0600000
• 包装等级：
  III
• 危险类别：
  6.1
• 安全说明：
  S20/21,S28,S45,S60,S61
• 储存条件：
  储存于阴凉、干燥、通风良好的库房中。远离火种和热源，避免阳光直射，并确保包装密封。与酸类及食用化学品分开存放，切忌混储。仓库内应备有合适的材料以处理可能的泄漏。

SDS

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Section 1. Chemical Product and Company Identification
Tetraphenylarsonium Chloride
Common Name/
Trade Name
Tetraphenylarsonium Chloride

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Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention.
Skin Contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention
immediately.
Serious Skin Contact Not available.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention immediately.
Serious Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation
when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.
Ingestion If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious Ingestion Not available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Not available.
Flammable Limits
Products of Combustion These products are carbon oxides (CO, CO2), halogenated compounds. Some metallic oxides.
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
Fire Fighting Media SMALL FIRE: Use DRY chemical powder.
and Instructions LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Not available.
Special Remarks on
Fire Hazards
Special Remarks on Explosion Not available.
Hazards

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Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
Tetraphenylarsonium Chloride

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Section 7. Handling and Storage
Precautions Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and
show the container or the label. Keep away from incompatibles such as oxidizing agents.
Storage Keep container tightly closed. Keep container in a cool, well-ventilated area.

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Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits TWA: 0.5 (mg(As)/m3)(as Arsenic) from OSHA (PEL) [United States]
TWA: 0.1 (mg(As)/m3)(as Arsenic) from ACGIH (TLV) [United States]
Consult local authorities for acceptable exposure limits.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. Odor Not available.
Not available.
Taste
Molecular Weight 418.8 g/mole
Not available.
Color
Not available.
pH (1% soln/water)
Boiling Point Not available.
258°C (496.4°F) - 260 C.
Melting Point
Critical Temperature Not available.
Specific Gravity Not available.
Vapor Pressure Not applicable.
Vapor Density Not available.
Not available.
Volatility
Odor Threshold Not available.
Water/Oil Dist. Coeff. Not available.
Ionicity (in Water) Not available.
Dispersion Properties Not available.
Solubility Not available.

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Section 10. Stability and Reactivity Data
Stability The product is stable.
Instability Temperature Not available.
Conditions of Instability Excess heat, incompatible materials
Incompatibility with various Reactive with oxidizing agents.
substances
Tetraphenylarsonium Chloride
Corrosivity Not available.
Special Remarks on Not available.
Reactivity
Special Remarks on Not available.
Corrosivity
Polymerization Will not occur.

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Section 11. Toxicological Information
Routes of Entry Inhalation. Ingestion.
Toxicity to Animals LD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects on No specific information is available in our database regarding the other toxic effects of this material for humans.
Humans
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on Not available.
Chronic Effects on Humans
Special Remarks on other Not available.
Toxic Effects on Humans

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Section 12. Ecological Information
Not available.
Ecotoxicity
BOD5 and COD Not available.
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the Products The products of degradation are as toxic as the product itself.
of Biodegradation
Special Remarks on the Not available.
Products of Biodegradation

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Section 13. Disposal Considerations
Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental
control regulations.

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Section 14. Transport Information
DOT Classification CLASS 6.1: Poisonous material.
Identification : Organoarsenic compounds, n.o.s (Tetraphenylarsonium chloride) UNNA: 3280 PG: II
Special Provisions for Not available.
Transport
Tetraphenylarsonium Chloride
DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
SARA 313 toxic chemical notification and release reporting: Arsenic compound (organic)
Federal and State
Regulations
California California prop. 65: This product contains the following ingredients for which the State of California has found
to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: No products were found.
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada) CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
Other Classifications
DSCL (EEC) R23/25- Toxic by inhalation and if S20/21- When using do not eat, drink or
swallowed. smoke.
S28- After contact with skin, wash immediately
with plenty of water.
S36/37- Wear suitable protective clothing and
gloves.
S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
Health Hazard
HMIS (U.S.A.) 3 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
3 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Tetraphenylarsonium Chloride
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

合成制备方法

暂无相关信息。

用途

暂无相关信息。

反应信息

• 作为反应物：
  描述：

  氯化四苯砷 在 氯 作用下， 反应 5.0h， 生成 trichlorures de tetraphenylarsonium
  参考文献：
  名称：

  Meyer, M. De; Levert, J. M.; Vanclef, A., Bulletin des Societes Chimiques Belges, 1983, vol. 92, # 8, p. 699 - 710

  摘要：

  DOI：
• 作为产物：
  描述：

  四苯基胂氯化物 在 盐酸 作用下， 生成 氯化四苯砷
  参考文献：
  名称：

  Mueller, Ulrich; Doerner, Hans-Dieter, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1982, vol. 37, # 2, p. 198 - 200

  摘要：

  DOI：
• 作为试剂：
  描述：

  苯乙烯 、 氯苯 在 t-di(μ-acetato)-bisPd2 氯化四苯砷 、 sodium acetate 作用下， 以 various solvent(s) 为溶剂， 反应 24.0h， 生成 1,1-二苯乙烯 、 顺式-二苯乙烯 、 反式-1,2-二苯乙烯
  参考文献：
  名称：

  非水离子液体中磷-四环烷催化的Heck反应

  摘要：

  磷-Paladacycles是用于Heck反应的最强大的钯催化剂体系。我们已经表明，使用非水离子液体（NAIL）替代传统分子溶剂进行该反应，其中的phospha-palladacycle催化剂易于分离产物，可能的催化剂循环利用，并进一步提高了催化剂的生产率。给出了用溴代和氯代芳烃获得的初步结果。

  DOI：

  10.1016/s0022-328x(98)00941-3

文献信息

• ATP3 and MTP3: Easily Prepared Stable Perruthenate Salts for Oxidation Applications in Synthesis
  作者：Peter W. Moore、Christopher D. G. Read、Paul V. Bernhardt、Craig M. Williams

  DOI：10.1002/chem.201800531

  日期：2018.3.26

  commercial catalyst supply. However, the mild instability of TPAP creates preparation, storage, and reaction reproducibility issues, due to unpreventable slow decomposition. In search of attributes conducive to catalyst longevity an extensive range of novel perruthenate salts were prepared. Subsequent evaluation unearthed a set of readily synthesized, bench stable, phosphonium perruthenates (ATP3 and

  该魔网格里菲斯四ñ丙基过钌酸铵（TPAP）催化剂已被合成界广泛采用，主要用于将醇氧化为醛和酮，还用于多种其他合成转化（例如二醇裂解，异构化，亚胺形成和杂环合成）。在广泛的反应范围，官能团耐受性，温和条件和商业催化剂供应上已经锻造了这种受欢迎度。但是，由于无法防止的缓慢分解，TPAP的轻度不稳定会导致制备，储存和反应重现性问题。为了寻找有利于催化剂寿命的属性，制备了多种新颖的过硼酸盐。随后的评估发现了一组易于合成，稳定的台式过氧化磷鎓（ATP3和MTP3），它们反映了TPAP的反应活性，
• Preparation and characterisation of dithiophosphinato-complexes of yttrium and the lanthanoids
  作者：A. Alan Pinkerton、Yisay Meseri、Charly Rieder

  DOI：10.1039/dt9780000085

  日期：——

  Hydrated lanthanoid(III) chlorides react with salts of dithiophosphinic acids in hot ethanolic solution to form the corresponding neutral tris or anionic tetrakis complexes, [Ln(S2PR2)3](R = C6H11) and [Ln(S2PR2)4]–(R = Me, OEt, or C6H11) respectively. The product of the reaction is sterically controlled. Displacement reactions with PPh3O to give mixed complexes are described. The characterisation, structures

  水合镧系元素（III）的氯化物与二硫代次膦酸盐在热乙醇溶液中反应，形成相应的中性三或阴离子四环配合物[Ln（S 2 PR 2）3 ]（R = C 6 H 11）和[Ln（S 2 PR 2）4 ] –（R = Me，OEt或C 6 H 11）。反应产物在空间上受到控制。PPh 3的置换反应描述了给出混合配合物的O。讨论了所有分离的配合物的表征，结构和光谱性质。将镧系元素-硫键与过渡金属-硫键进行比较
• 5‐Methylthiophene‐2,3‐dithiolene Transition Metal Complexes
  作者：Ana I. S. Neves、Isabel C. Santos、Joana T. Coutinho、Laura C. J. Pereira、Rui T. Henriques、Elsa B. Lopes、H. Alves、Manuel Almeida、Dulce Belo

  DOI：10.1002/ejic.201402048

  日期：2014.8

  [Cu4(α-mtpdt)3]2–, the metals form complexes of the general formula [M(α-mtpdt)2]. With Au, Ni and Fe, the complexes are directly obtained from the synthesis as monoanionic salts, and the isostructural crystal structures of [nBu4N][Ni(α-mtpdt)2] and [nBu4N][Au(α-mtpdt)2] were solved by single-crystal X-ray diffraction. For M = Co, Pt and Pd, both monoanionic and dianionic salts were obtained, and the

  基于新配体 5-甲基噻吩-2,3-二硫醇 (α-mtpdt) 和 Au、Ni、Fe、Co、Cu、Pt 和 Pd 的过渡金属配合物被制备为四烷基铵和四芳基鏻盐，并通过循环伏安法、X-射线衍射、电子顺磁共振 (EPR) 光谱和磁化率测量。除了形成四金属簇[Cu4(α-mtpdt)3]2-的Cu配合物外，金属形成通式[M(α-mtpdt)2]的配合物。与Au、Ni和Fe配合物直接合成为单阴离子盐，[nBu4N][Ni(α-mtpdt)2]和[nBu4N][Au(α-mtpdt)2]等结构晶体结构由单晶 X 射线衍射解决。对于 M = Co、Pt 和 Pd，获得了单阴离子盐和双阴离子盐，[Ph4As]2[Co(α-mtpdt)2]和[Ph4As]2[Pd(α-mtpdt)2]的晶体结构由单晶X射线衍射确定。Co 化合物呈现出罕见的四面体配位几何结构。单阴离子 Ni 和 Au 配合物与碘的氧化产生稳
• Mechanistic Insight into the Protonolysis of the Pt−C Bond as a Model for C−H Bond Activation by Platinum(II) Complexes
  作者：Raffaello Romeo、Giuseppina D'Amico

  DOI：10.1021/om060217n

  日期：2006.7.1

  The kinetic and NMR features of the protonolysis reactions on platinum(II) alkyl complexes of the types cis-[PtMe2L2], [PtMe2(L-L)], cis-[PtMeClL2], and [PtMeCl(L-L)] (L = PEt3, P(Pri)3, PCy3, P(4-MePh)3, L-L = dppm, dppe, dppp, dppb) in methanol suggest a rate-determining proton attack at the Pt−C bond. In contrast, a multistep oxidative-addition−reductive-elimination mechanism characterizes the methane

  顺式-[PtMe 2 L 2 ]，[PtMe 2（LL）]，顺式-[PtMeClL 2 ]和[PtMeCl（LL）]的铂（II）烷基络合物的质子分解反应的动力学和NMR特征。（L = PEt 3，P（Pr i）3，PCy 3，P（4-MePh）3，LL = dppm，dppe，dppp，dppb）在甲醇中显示出决定Pt-C键质子进攻的速率。相比之下，多步氧化加减还原机理表征了相应反式-[PtMeClL 2的质子化过程中的甲烷损失] 物种。在暗示这两个系统的不同反应途径方面具有特殊诊断性的工具是（i）动力学氘同位素实验的结果不同（ii）低温1 H NMR检测或不检测Pt（IV）氢化烷基中间产物实验，以及（iii）检测或不存在同位素加扰以及将氘掺入Pt-CH 3中，并损失一定范围的CH n D n - 4异构体。对于所有系统，质子分解的速度受配体空间拥塞的阻碍，受配体电子的贡献而加速，并且几乎
• Ni complexes of N 2 S ligands with amine/imine and amine/amide donors with relevance to the active site of Ni superoxide dismutase
  作者：Nilmini K. Senaratne、Tom M. Mwania、Curtis E. Moore、David M. Eichhorn

  DOI：10.1016/j.ica.2018.02.006

  日期：2018.5

  introducing the thiolate into the tridentate ligands. The two ligands and series of complexes feature the N2S2 coordination environment found at the active site of Ni superoxide dismutase and differ only in the identity of one of the N donors (imine vs. amide). Those with the amide N donor contain the exact donor set present in reduced Ni superoxide dismutase. The complexes have been characterized by X-ray crystallography

  摘要一系列[Ni（NNImS）（RS）]形式的Ni络合物（NNImS =（2-（N-（二甲基氨基乙基）亚氨基甲基）苯硫醇酯; R =苯基，4-硝基苯基，4-氟苯基，4-氯苯基， 4-叔丁基苯基，叔丁基），以及两种形式为[Ni（NNAmS）（RS）]-（NNAmS = 2-（N-（二甲基氨基乙基）氨基羰基）苯硫醇酯的络合物; R =苯基，4-硝基苯基）分别以2,2'-二硫代二甲醛和2,2'-二硫代二苯甲酰氯为合成基团合成，将硫醇盐引入三齿配体中。这两个配体和一系列配合物具有在活性位点上存在的N2S2配位环境。镍超氧化物歧化酶的组成不同，只是N供体之一的亚胺（亚胺和酰胺）的身份不同，酰胺N供体的那些具有还原的镍超氧化物歧化酶中存在的确切供体。 配合物已经通过X射线晶体学，电子光谱学和电化学进行了表征。

表征谱图