4-methyl-2-(2,4,5-triphenyl-1H-imidazol-1-yl)benzo[d]thiazole | 1359841-69-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-methyl-2-(2,4,5-triphenyl-1H-imidazol-1-yl)benzo[d]thiazole
• 英文别名: 4-Methyl-2-(2,4,5-triphenylimidazol-1-yl)-1,3-benzothiazole；4-methyl-2-(2,4,5-triphenylimidazol-1-yl)-1,3-benzothiazole
• CAS: 1359841-69-2
• 化学式: C₂₉H₂₁N₃S
• 分子量: 443.572
• InChiKey: RSTBTRSOQKHIDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  59
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氨基-4-甲基苯并噻唑 、 苯甲醛 、 联苯甲酰 在 ammonium acetate 作用下， 以 乙腈 为溶剂， 以72%的产率得到4-methyl-2-(2,4,5-triphenyl-1H-imidazol-1-yl)benzo[d]thiazole
  参考文献：
  名称：

  A novel bioglycerol-based recyclable carbon catalyst for an efficient one-pot synthesis of highly substituted imidazoles

  摘要：

  The new bioglycerol-based carbon catalyst acts as an efficient, readily available, and reusable catalyst for the synthesis of 2,4,5-trisubstituted imidazoles/1,2,4,5-tetrasubstituted imidazoles, when aromatic aldehyde, ammonium acetate/amine, and 1,2-diketone are reacted in acetonitrile. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.12.092

文献信息

• A novel bioglycerol-based recyclable carbon catalyst for an efficient one-pot synthesis of highly substituted imidazoles
  作者：K. Ramesh、S. Narayana Murthy、K. Karnakar、Y.V.D. Nageswar、Kukuma Vijayalakhshmi、Bethala L.A. Prabhavathi Devi、R.B.N. Prasad

  DOI：10.1016/j.tetlet.2011.12.092

  日期：2012.2

  The new bioglycerol-based carbon catalyst acts as an efficient, readily available, and reusable catalyst for the synthesis of 2,4,5-trisubstituted imidazoles/1,2,4,5-tetrasubstituted imidazoles, when aromatic aldehyde, ammonium acetate/amine, and 1,2-diketone are reacted in acetonitrile. (C) 2011 Elsevier Ltd. All rights reserved.